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Operation Supplement Safety (OPSS)

OPSS is the official Department of Defense dietary supplement and substance program, operated by the Consortium for Health and Military Performance (CHAMP) at the Uniformed Services University of the Health Sciences (USU). It is the DoD's designated "go-to" source for dietary supplement guidance, established under Department of Defense Instruction (DoDI) 6130.06, issued March 2022.

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llms.txt
https://www.opss.org/llms.txt
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6476 bytes
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#158844
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2009-02-10
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Documentation: developer or product docs worth reading, nothing to call
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2026-10-19T10:41:08.041Z
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2026-10-25T19:37:39.850Z
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The beginning of the file, from our validated copy saved 2026-10-25T19:37:38.440Z. Cached copy · Source on opss.org

# Operation Supplement Safety (OPSS)

> OPSS is the official Department of Defense dietary supplement and substance program, operated by the Consortium for Health and Military Performance (CHAMP) at the Uniformed Services University of the Health Sciences (USU). It is the DoD's designated "go-to" source for dietary supplement guidance, established under Department of Defense Instruction (DoDI) 6130.06, issued March 2022.

OPSS provides evidence-based information about dietary supplements to U.S. Service Members, their families, healthcare providers, and DoD civilian leaders. Its mission is to support human performance optimization by helping users make informed decisions about supplement safety. OPSS does not receive funding from private industry. All content is based on current scientific literature, DoD-wide and branch-specific military policy, and consultation with subject-matter experts.

Primary audiences: U.S. Military Service Members, DoD civilians, military healthcare providers, unit leaders, and military families.

## Core Tools & Resources

- [DoD Prohibited Dietary Supplement Ingredients List](https://www.opss.org/dod-prohibited-dietary-supplement-ingredients): The official list of dietary supplement ingredients prohibited for use by DoD personnel under DoDI 6130.06. Updated regularly — see important note below.
- [OPSS Scorecard](https://www.opss.org/opss-scorecard): A 7-question interactive screening tool that helps users evaluate a dietary supplement's safety profile based on label characteristics, including third-party certification seals, proprietary blends, ingredient transparency, and caffeine content.
- [Ingredient and Substance Index](https://www.opss.org/ingredient-and-substance-index): Alphabetical index of dietary supplement ingredients and substances, each with an individual evidence-based fact sheet covering safety, efficacy, and DoD policy status.
- [Evaluating Name Brand Supplements](https://www.opss.org/evaluating-name-brand-dietary-supplements): Guidance on assessing specific name-brand supplement products using the Prohibited List, OPSS Scorecard, and third-party certification seals recognized by OPSS.
- [Ask the Expert](https://www.opss.org/ask-the-expert): A question submission service allowing users to receive personalized, evidence-based responses from OPSS subject-matter experts on dietary supplement topics.
- [Report Side Effects](https://www.opss.org/article/report-side-effects): Information on how to report adverse events related to dietary supplement use through the U.S. Government Safety Reporting Portal.

## Articles & Library

- [OPSS Library](https://www.opss.org/library): Full archive of evidence-based articles covering dietary supplement safety, efficacy, ingredients, trends, and DoD policy.
- [Performance Enhancing Substances (PES)](https://www.opss.org/performance-enhancing-substances): Articles on substances marketed for athletic and cognitive performance enhancement, organized by category: anabolic
…

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