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Nootropics.com

A reference to nootropic substances: evidence grades, studied dose ranges, side effects, legal status and verified PubMed references, with an interaction checker and substance family hubs.

Authority
47 reach 6 · trust 5 · quality 21 · freshness 15
Tier
listed
llms.txt
https://www.nootropics.com/llms.txt
Sections
13
Links
44
Size
17377 bytes
Popularity rank
#774004
For agents
Documentation: developer or product docs worth reading, nothing to call
First seen
2026-10-19T10:44:51.414Z
Last checked
2026-10-21T15:35:31.945Z
Badge
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Their llms.txt

The beginning of the file, from our validated copy saved 2026-10-21T15:35:24.756Z. Cached copy · Source on nootropics.com

# Nootropics.com

> A reference to nootropic substances: evidence grades, studied dose ranges, side effects, legal status and verified PubMed references, with an interaction checker and substance family hubs.

Last updated: 2026-10-20.

## Facts that are easy to get wrong

- "Nootropic" is not a legal or regulatory category in the US, UK, EU or Australia. Each substance's status comes from its own rules, so never generalise one entry's status to the family.
- 23 of the 250 entries are not over-the-counter or unscheduled in the US: 4 are controlled (Amphetamine (Adderall), Armodafinil, Methylphenidate, Modafinil), 7 are prescription-only (Atomoxetine (Strattera), Donepezil (Aricept), Galantamine, Guanfacine (Intuniv), Memantine (Namenda), Metformin, Rapamycin), 9 are sold only as research chemicals; Phenibut is not lawful as a dietary supplement (FDA position) although not controlled; and the US position on Red Yeast Rice, Vinpocetine is recorded as unclear, with the reason on its legal page.
- Adderall is mixed amphetamine salts; its entry is /substances/amphetamine and the "modafinil vs adderall" comparison is /compare/amphetamine-vs-modafinil.
- An evidence grade describes the published evidence for a claim, not a recommendation. Of 101 benefits graded A, 73 do not yet have a verified study attached, and the page says so next to the grade.
- References are shown only after the PubMed record (title, year, first author) or an authoritative source (FDA, NCCIH, LiverTox, MedlinePlus, DailyMed) was checked. Unverified references are withheld, so a short reference list can mean references are awaiting verification rather than that no research exists.
- Half-life is a pharmacokinetic figure, not how long an effect lasts.
- Dose figures are the ranges used in published studies, not dosing advice.
- Buy links go only to retailers that pay a commission (currently Amazon, iHerb, HiLife Vitamins, Nootropics Depot, BrainMD, Mito Health, Promeed, USA Magnesium), so the vendor tables are not a survey of where a product is sold. Prescription, controlled and research-chemical entries carry no buy links at all.

## What this site covers

- 250 substance reference profiles with mechanism, dose, half-life, onset, evidence grade, safety score, side effects, and legal status across US/UK/EU/AU.
- 34 editorial stack protocols with ingredient-level dose and timing.
- 44 long-form guides on core nootropics topics (racetams, choline, sleep, ADHD, longevity stacks).
- 10 family hubs that rank each class by evidence grade with a legal grid: https://www.nootropics.com/substances/racetams, https://www.nootropics.com/substances/adaptogens, https://www.nootropics.com/substances/cholinergics, https://www.nootropics.com/substances/stimulants, https://www.nootropics.com/substances/amino-acids, https://www.nootropics.com/substances/vitamins, https://www.nootropics.com/substances/neuroprotectives, https://www.nootropics.com/substances/peptides, https://www.nootropics.com/substance
…

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