nextconsensus.com valid
NextConsensus
NextConsensus estimates the probability that guideline bodies, regulators, and payers will act on changing medical evidence before your review deadline.
Their llms.txt
The beginning of the file, from our validated copy saved 2026-10-26T16:57:39.810Z. Cached copy · Source on nextconsensus.com
# NextConsensus
> NextConsensus estimates the probability that guideline bodies, regulators, and payers will act on changing medical evidence before your review deadline.
NextConsensus provides dated evidence histories and registered forecasts for defined guideline, label, and coverage decisions.
Each entry below is a page's own title and description, listed in the order of the sitemap. Full page text: https://nextconsensus.com/llms-full.txt
## Registered forecasts
- [Registered forecasts](https://nextconsensus.com/forecast/): Probabilities for FDA approvals by PDUFA date, NICE guidance by scheduled date, and NCCN listings, registered before the outcome under a rule that settles each.
- [PDUFA calendar 2026–2027: FDA goal dates with registered forecasts](https://nextconsensus.com/pdufa-calendar/): FDA PDUFA goal dates for 27 applications, by month: the drug, the applicant, the review center, and a probability of approval registered before each date.
- [NICE appraisal calendar 2026–2027: expected dates with registered forecasts](https://nextconsensus.com/nice-appraisal-calendar/): Expected NICE publication dates for 23 technology appraisals, by month: NICE's title, project ID and committee, and a probability registered before each date.
- [75% forecast: NCCN lists sunvozertinib as a first-line option in EGFR exon 20 insertion NSCLC](https://nextconsensus.com/forecast/ff-001/): Registered 2026-08-17, before the outcome was known, at 75%, against a base rate of 62%. The rule that settles it is public; event by 2027-07-31.
- [88% forecast: FDA approves a first-line indication for sunvozertinib in EGFR exon 20 insertion NSCLC](https://nextconsensus.com/forecast/ff-002/): Registered 2026-09-22, before the outcome was known, at 88%, against a base rate of 85%. The rule that settles it is public; event by 2027-07-31.
- [55% forecast: FDA approves first-line sunvozertinib in EGFR exon 20 insertion NSCLC on or before 2027-03-31](https://nextconsensus.com/forecast/ff-003/): Registered 2026-09-22, before the outcome was known, at 55%, against a base rate of 60%. The rule that settles it is public; event by 2027-03-31.
- [45% forecast: FDA first-line approval of sunvozertinib precedes the NCCN first-line listing](https://nextconsensus.com/forecast/ff-004/): Registered 2026-09-22, before the outcome was known, at 45%, against a base rate of 50%. The rule that settles it is public; event by 2027-07-31.
- [82% forecast: FDA approves the aficamten MAPLE-HCM supplement to NDA 219083 on or before the disclosed PDUFA goal date of 2026-11-14](https://nextconsensus.com/forecast/ff-005/): Registered 2026-09-26, before the outcome was known, at 82%, against a base rate of 85%. The rule that settles it is public; event by 2026-11-14.
- [85% forecast: FDA approves BBP-418 for limb-girdle muscular dystrophy type 2I/R9 on or before the disclosed PDUFA goal date of 2026-11-27](https://nextconsensus.com/forecast/ff-006/): Registered 2026-09-26, before the outcome was kno
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