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LINEA System

Clinical trial intelligence platform. The Research Site Index (RSI) scores 248,000+ investigators across 186 countries and 181 specialties. AcceleTrial is the site-selection and engagement platform, built on the deterministic Research Site Index.

For agents: Clinical trial intelligence company; Research Site Index scores 248,000+ investigators and AcceleTrial platform for site selection and engagement.

clinical trialssite selectioninvestigator databaseresearch site indexpatient recruitment

Their llms.txt

The beginning of the file, from our validated copy saved 2026-10-25T12:01:50.027Z. Cached copy · Source on lineasystem.com

# LINEA System

> Clinical trial intelligence platform. The Research Site Index (RSI) scores 248,000+ investigators across 186 countries and 181 specialties. AcceleTrial is the site-selection and engagement platform, built on the deterministic Research Site Index.

This file follows the [llms.txt](https://llmstxt.org) specification. Every page is also available as clean markdown at `{slug}.md`.

## Platform

- [RSI](https://www.lineasystem.com/rsi.md): The Research Site Index scores 248,000+ clinical trial investigators across 186 countries and 181 specialties. Deterministically scored, protocol-aware, updated monthly.
- [AcceleTrial](https://www.lineasystem.com/acceletrial.md): AcceleTrial is LINEA's site selection and engagement platform, built on the deterministic Research Site Index. Faster site activation, more reliable patient contribution, less site burden.

## Company

- [About](https://www.lineasystem.com/about.md): LINEA System is a clinical trial intelligence company founded in 2008 by Kathleen Colatrella. Our mission: replace guesswork in site selection with verified performance data.

## Case Studies

- [ACS Case Study](https://www.lineasystem.com/case-study-acs.md): ACS case study: how LINEA's investigator intelligence accelerated site selection and enrollment for an acute coronary syndrome trial.
- [MS Case Study](https://www.lineasystem.com/case-study-ms.md): MS case study: applying the Research Site Index to a multiple sclerosis trial, with results on site activation velocity and enrollment quality.
- [MS Vaccine Case Study](https://www.lineasystem.com/case-study-ms-vaccine.md): MS Vaccine case study: sponsor-side results from applying AcceleTrial to a multiple-sclerosis vaccine program.
- [PBC Case Study](https://www.lineasystem.com/case-study-pbc.md): PBC case study: primary biliary cholangitis trial site selection outcomes using LINEA's investigator intelligence platform.

## Resources

- [Clinical Intelligence Briefing](https://www.lineasystem.com/briefing.md): The Clinical Signal: a weekly briefing on clinical trials, AI in healthcare, and drug development.
- [Resources](https://www.lineasystem.com/resources.md): Case studies, guides, and white papers on clinical trial site selection, investigator intelligence, and AI in clinical research.
- [AI Integration Playbook](https://www.lineasystem.com/playbook-ai.md): The AI Site Selection Playbook: a practical guide for sponsors and CROs using AI to accelerate site activation and patient recruitment.

## Guides

- [Common Questions Guide for AcceleTrial](https://www.lineasystem.com/guide-acceletrial-faq.md): Frequently asked questions about AcceleTrial, covering platform capabilities, integration, implementation timeline, and sponsor outcomes.
- [Measuring Site Selection ROI: A Framework for Clinical Operations Leaders](https://www.lineasystem.com/guide-site-selection-roi.md): How to calculate ROI from AI-driven site selection. Framework covering activation speed, enrollment, scre
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