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Interaction Checker (interaction-checker.com)

Free drug interaction checker. Every result quotes the FDA prescribing label sentence it came from, with a DailyMed link. Covers prescription and OTC drugs plus supplements, vitamins, foods, alcohol, tobacco, and cannabis. No account, no ads, no tracking; the medication list stays in the browser.

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Authority
46 reach 6 · trust 5 · quality 20 · freshness 15
Tier
listed
llms.txt
https://interaction-checker.com/llms.txt
llms-full.txt
https://interaction-checker.com/llms-full.txt
Sections
7
Links
0
Size
4689 bytes
Popularity rank
#752051
Registered
2026-09-04
Country
— Publisher location unknown; CDN address excluded
Country evidence
No published address evidence collected yet
First seen
2026-10-25T16:34:49.141Z
Last checked
2026-10-25T18:37:19.469Z
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Their llms.txt

The beginning of the file, from our validated copy saved 2026-10-25T18:37:17.377Z. Cached copy · Source on interaction-checker.com

# Interaction Checker (interaction-checker.com)

> Free drug interaction checker. Every result quotes the FDA prescribing label sentence it came from, with a DailyMed link. Covers prescription and OTC drugs plus supplements, vitamins, foods, alcohol, tobacco, and cannabis. No account, no ads, no tracking; the medication list stays in the browser.

## Method
- Source: FDA prescribing labels via openFDA/DailyMed (public domain); NIH ODS, NCCIH, FDA, and NIAAA fact sheets for supplement/food/alcohol rules.
- Matching: whole-word search of each label's boxed warning, contraindications, warnings, and drug interactions sections for the other drug's name or drug class, in both directions.
- Severity: Major (boxed warning, contraindications, or wording such as contraindicated/avoid/not recommended), Moderate (monitor/dose/adjust wording), Minor (plain mention), No significant interaction (label explicitly reports none).

## Pages
- /                     The checker (client-side; supports ?d=id1,id2 links)
- /drugs                Drugs A to Z
- /drugs/<id>           Every documented interaction for one drug
- /drugs/<id>/pills     What the drug looks like: every tablet/capsule version in its FDA labels (imprint, color, shape, size, labeler) with rendered images
- /drugs/<id>/facts     Sourced facts, community claims with evidence status, common misconceptions, and FAQ (every line cites its source)
- /pills                Pill images by drug
- /supplements          Supplements, food, and alcohol
- /supplements/<id>     Every drug label mentioning that item, plus curated rules
- /interactions/<a>-and-<b>   One pair, all quotes, both labels
- /guide                How drug interactions work
- /guides               Reference guides on the label data: serotonin syndrome, opioids with benzodiazepines and other sedatives, QT prolongation, bleeding risk, alcohol, grapefruit, and the 2026 report on interaction warnings in FDA labels
- /guides/<slug>.md     Each guide as plain markdown, same words and numbers as the page
- /about                Method, sources, limits, data dates, FAQ
- /disclaimer           Medical disclaimer

## Languages
- Every page above except /disclaimer exists in English (no prefix) and under /fr /es /de /pt /pl /id /tr /ar /hi (for example /es/interactions/<a>-and-<b>). Slugs are the same in every language.
- Drug names are shown as each language writes them (paracetamol for acetaminophen outside the US). A label sentence shown in translation always has the English FDA original beside it; the English sentence is the evidence.

## Free API and MCP server (no key, no auth)
- /api                  Developer docs for the REST API
- /api/v1               API index (JSON): endpoints, limits, data dates
- /api/v1/openapi.json  OpenAPI 3.1 description
- /api/v1/checks?items=lisinopril,ibuprofen   Every pair among the items with severity and verbatim label quotes (GET or POST {"items":[...]})
- /api/v1/substances?q=advil                  Typo-toler
…

Machine-readable: GET /v1/resolve?q=interaction-checker.com · GET /v1/domain/interaction-checker.com · this page as Accept: application/json or text/markdown · MCP lookup_domain

Automatically discovered from public files. Inclusion does not imply endorsement or publisher participation.

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