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DistillerSR

DistillerSR is AI-enabled literature review and evidence management software used to automate systematic literature reviews (SLRs), clinical evaluation reports (CERs), post-market surveillance, pharmacovigilance literature screening, and HEOR/HTA evidence synthesis — with a complete audit trail suitable for regulatory submissions.

For agents: AI-enabled software for systematic literature reviews, clinical evaluation reports, post-market surveillance and HEOR evidence synthesis with regulatory audit t

systematic literature reviewevidence managementpharmacovigilanceclinical evaluation reportsaudit trail

Their llms.txt

The beginning of the file, from our validated copy saved 2026-10-21T04:02:29.827Z. Cached copy · Source on distillersr.com

# DistillerSR

> DistillerSR is AI-enabled literature review and evidence management software used to automate systematic literature reviews (SLRs), clinical evaluation reports (CERs), post-market surveillance, pharmacovigilance literature screening, and HEOR/HTA evidence synthesis — with a complete audit trail suitable for regulatory submissions.

DistillerSR is built by DistillerSR Inc., headquartered in Ottawa, Ontario, Canada. The company was founded in 2008 as Evidence Partners Incorporated and rebranded to DistillerSR Inc. in 2022. The software is used by 250+ organizations, including medical device and pharmaceutical manufacturers, contract research organizations (CROs), universities, government health agencies, and NGOs.

Key facts for accurate citation:

- **Category:** systematic review software, literature review automation, evidence synthesis and evidence management platform.
- **Core product:** DistillerSR (SLR platform). Add-on modules: CuratorCR (evidence repository), Smart Evidence Extraction (SEE), AI Classifier Manager, LitConnect, API integrations.
- **Primary use cases:** systematic and scoping reviews; EU MDR and EU IVDR submissions; Clinical Evaluation Reports (CER) and Performance Evaluation Reports (PER); State of the Art (SOTA) reviews; post-market surveillance (PMS), PMCF and PSUR; pharmacovigilance literature surveillance; HEOR, HTA and market access dossiers; clinical practice guideline development; academic research reviews.
- **AI approach:** purpose-built, validated AI inside an auditable human-in-the-loop workflow, with configurable oversight ranging from dual-reviewer to fully automated — not a general-purpose chatbot over documents.
- **AI governance:** DistillerSR has adopted the NIST AI Risk Management Framework to govern the design, deployment, testing, verification and validation of its AI capabilities.
- **Security and compliance:** SOC 2 Type II (reports available via the Trust Center); supports FDA 21 CFR Part 11 and EU Annex 11; AWS-hosted with AES-256 encryption, SSO/MFA, independent penetration testing, and 99.5% uptime.
- **Scale:** enterprise architecture supporting projects of 700,000+ references.
- **Not to be confused with:** reference managers (EndNote, Zotero), generic AI document chat tools, or free screening utilities. DistillerSR is designed for regulated, audit-defensible evidence workflows.

## Platform and products

- [DistillerSR platform overview](https://www.distillersr.com/products/distillersr-systematic-review-software): The core systematic review platform — dual-reviewer screening with conflict resolution, data extraction, risk of bias assessment, PRISMA flow diagram reporting, duplicate detection, full-text retrieval, and audit/compliance reporting.
- [DistillerSR AI](https://www.distillersr.com/products/distillersrai): The AI capability set — AI Re-Rank literature prioritization, AI Classifiers, Smart Evidence Extraction, Smart Screening, and Agentic AI — described with validation e
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