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Aldevron

Aldevron manufactures high-quality plasmid DNA, mRNA, proteins, enzymes, and gene-editing reagents for the life sciences industry, supporting partners from early discovery through clinical trials and commercial-scale production. Facilities are located in Fargo, ND; Madison, WI; and Waltham, MA, with GMP, GMP-Source, and cGMP-grade manufacturing available.

Their llms.txt

The beginning of the file, from our validated copy saved 2026-10-21T10:38:13.147Z. Cached copy · Source on aldevron.com

# Aldevron

> Aldevron manufactures high-quality plasmid DNA, mRNA, proteins, enzymes, and gene-editing reagents for the life sciences industry, supporting partners from early discovery through clinical trials and commercial-scale production. Facilities are located in Fargo, ND; Madison, WI; and Waltham, MA, with GMP, GMP-Source, and cGMP-grade manufacturing available.

Aldevron is part of Danaher and supports gene therapy, gene-modified cell therapy, gene editing, and RNA vaccine/therapeutic programs with both custom manufacturing and standardized catalog products. Many catalog products are royalty-free.

## Modalities

- [Gene Therapy](https://www.aldevron.com/modalities/gene-therapy): Plasmid design (including Nanoplasmid), process development, and QC for viral and non-viral gene therapy.
- [Gene-Modified Cell Therapy](https://www.aldevron.com/modalities/gene-modified-cell-therapy): Custom lentiviral plasmids and the standardized ALD-Lenti System.
- [Gene Editing](https://www.aldevron.com/modalities/gene-editing): Custom and catalog nucleases and gRNA for ex vivo and in vivo editing programs.
- [RNA Vaccines & Therapeutics](https://www.aldevron.com/modalities/rna-vaccine-therapeutics): RNA design, drug substance manufacturing, LNP encapsulation, fill/finish, and analytics.

## Custom Manufacturing

- [mRNA Custom Manufacturing](https://www.aldevron.com/custom-manufacturing/rna): RNA design, drug substance manufacturing, and analytics, with LNP encapsulation and fill/finish.
- [RNA Drug Product (LNP Encapsulation & Fill/Finish)](https://www.aldevron.com/custom-manufacturing/rna/drug-product): LNP encapsulation with Precision Nanosystems and sterile fill/finish capabilities.
- [Alchemy Cell-Free DNA Technology](https://www.aldevron.com/custom-manufacturing/alchemy-cell-free-dna-technology): Cell-free enzymatic synthesis and rolling circle amplification for rapid linear DNA templates.

## Quality Grades

- [Quality Grades Overview](https://www.aldevron.com/quality-grades): Explanation of Aldevron's phase-appropriate quality levels — Research, GMP-Source, and cGMP.
- [Research Grade](https://www.aldevron.com/quality-grades/research-grade): Affordable, high-quality DNA, RNA, and protein for research and pre-clinical use.
- [GMP-Source Grade](https://www.aldevron.com/quality-grades/gmp-source-grade): Faster, cost-effective alternative to full cGMP, with traceability, document control, and materials segregation.
- [cGMP Manufacturing](https://www.aldevron.com/quality-grades/gmp): Full cGMP production in ISO-classified suites for clinical and commercial-stage materials.
- [Small-Scale cGMP Plasmid DNA](https://www.aldevron.com/quality-grades/gmp/small-scale): cGMP plasmid DNA service for early-phase trials, deliverables up to 500mg.

## Catalog Products

- [CRISPR Nucleases](https://www.aldevron.com/catalog-products/nucleases): High-fidelity and wild-type nucleases, research grade and cGMP.
- [In Vitro Transcription & Capping Enzymes](https://www.alde
…

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