# Metabolon: Small Molecules, Big Insights™ > Metabolon uses metabolomics to provide biological insights to answer the toughest questions in life sciences research and drug development\. Generated by Yoast SEO v28.7, this is an llms.txt file, meant for consumption by LLMs. ## Pages - [From Perturbed Metabolites to Prioritized Protein Candidates](https://www.metabolon.com/bioinformatics-software/splash-and-ripple/): Metabolon’s Splash \& Ripple workflow works backward from the metabolomic readout, connecting perturbed metabolites to the proteins most likely to explain the observed biological response\. - [Metabolon Homepage](https://www.metabolon.com/): Metabolon uses metabolomics to provide biological insights to answer the toughest questions in life sciences research and drug development\. - [Bioinformatics Software](https://www.metabolon.com/bioinformatics-software/): Metabolon's Integrated Bioinformatics Platform is your unparalleled solution for metabolomics research\. Supported by Metabolon’s proprietary metabolite library, robust analytical tools, and reporting visualizations, you can collaborate with teams across the world to gain biological insights into your data\. - [Principal Component Analysis \(PCA\)](https://www.metabolon.com/bioinformatics-software/pca/): The Principal Component Analysis \(PCA\) tool illuminates your data’s global landscape, guiding you to dive deeper where it matters\. - [Partial Least Squares Discriminant Analysis \(PLS\-DA\)](https://www.metabolon.com/bioinformatics-software/pls-da/): PLS\-DA plays a pivotal role in metabolomics analysis, providing a powerful statistical framework for unraveling complex relationships within high\-dimensional datasets\. ## Posts - [Gut\-Derived Metabolites in CKD: From Microbiome to Mechanism to Medicine](https://www.metabolon.com/blog/gut-derived-metabolites-in-ckd-from-microbiome-to-mechanism-to-medicine/): While chronic kidney disease is traditionally managed through blood pressure control and dialysis, a growing body of evidence shows that gut microbiota and its metabolites actively contribute to CKD progression and its comorbidities\. - [Inside Metabolon Lab Operations: Scaling Metabolomics with Quality and Reproducibility: An interview with Leane Woody, Director of Lab Operations at Metabolon](https://www.metabolon.com/blog/inside-metabolon-lab-operations-scaling-metabolomics-with-quality-and-reproducibility-an-interview-with-leane-woody-director-of-lab-operations-at-metabolon/) - [The Metabolon Verus™ Metabolomics Profiling Kit: The easiest way to put metabolomics into your multiomics](https://www.metabolon.com/blog/the-metabolon-verus-metabolomics-profiling-kit-the-easiest-way-to-put-metabolomics-into-your-multiomics/) - [Metabolon Expands Microbiome Panel to Strengthen Industry Leadership in Functional Microbiome Research](https://www.metabolon.com/press/metabolon-expands-microbiome-panel-to-strengthen-industry-leadership-in-functional-microbiome-research/) - [Metabolon Delivers Large\-Scale Metabolomics Dataset to Genomics England's 100,000 Genomes Project to Advance Rare Disease Research ](https://www.metabolon.com/press/metabolon-delivers-large-scale-metabolomics-dataset-to-genomics-englands-100000-genomes-project/) ## Resources - [Splash \& Ripple Technical Whitepaper](https://www.metabolon.com/resources/type/white-papers/splash-and-ripple-technical-whitepaper/): Splash \& Ripple returns a ranked, evidence\-linked candidate\-gene table from a perturbed metabolite profile\. It acts as an informed search\-space reducer to developer mechanistic hypotheses and follow\-up experiments\. Download the technical whitepaper to learn more about the Splash \& Ripple workflow\. - [Splash \& Ripple ASHG 2026 Poster](https://www.metabolon.com/resources/posters/splash-and-ripple-ashg-2026-poster/): Splash \& Ripple returns a ranked, evidence\-linked candidate\-gene table from a perturbed metabolite profile\. It acts as an informed search\-space reducer to developer mechanistic hypotheses and follow\-up experiments\. Download this overview poster to learn more about the Splash \& Ripple workflow\. - [Splash \& Ripple NextGen Omics 2026 Poster](https://www.metabolon.com/resources/posters/splash-ripple-nextgen-omics-2026-poster/): Splash \& Ripple returns a ranked, evidence\-linked candidate\-gene table from a perturbed metabolite profile\. It acts as an informed search\-space reducer to developer mechanistic hypotheses and follow\-up experiments\. Download this overview poster to learn more about the Splash \& Ripple workflow\. - [Splash \& Ripple Case Study](https://www.metabolon.com/resources/case-studies/splash-ripple-university-of-pretoria-case-study/): Researchers at the University of Pretoria wanted to understand the drivers of severity in hypoxic ischemic encephalopathy \(HIE\)\. Metabolomics paired with Splash \& Ripple helped to reveal the dynamic nature of severity in HIE, and the potential mediators involved\. - [eBrochure: Sample Matrix Validation and Method Development](https://www.metabolon.com/resources/type/product-literature/metabolon-custom/): With more than 20 years of experience and continuous innovation, Metabolon has created the industry’s most advanced system for measuring and understanding the metabolome\. Learn more about Metabolon's services in this brochure\. ## Events - [Society for Neuroscience \(SfN\) 2026 Annual Meeting](https://www.metabolon.com/events/society-for-neuroscience-sfn-annual-meeting-2026/) - [AASLD The Liver Meeting 2026](https://www.metabolon.com/events/aasld-the-liver-meeting-2026/) - [ASHG 2026](https://www.metabolon.com/events/ashg-2026/) - [ABRF NERLSCD Northeast Chapter 2026](https://www.metabolon.com/events/abrf-nerlscd-northeast-chapter-2026/) - [Biomarkers EU 2026](https://www.metabolon.com/events/biomarkers-eu-2026/) ## News - [Metabolon Announces New Bioinformatics Application to Translate Metabolomic Biomarkers into Actionable Multiomic Hypotheses](https://www.metabolon.com/news/metabolon-launches-new-bioinformatics-application-to-translate-metabolomic-biomarkers-into-actionable-multiomic-hypotheses/): Metabolon, Inc\. announces the launch of Splash \& Ripple, a new bioinformatics application within the company's Integrated Bioinformatics Platform\. Splash \& Ripple helps researchers translate metabolomic biomarkers into candidate protein mechanisms and actionable multiomic hypotheses\. - [Metabolon Verus™ Metabolomics Profiling Kit Now Available to Order](https://www.metabolon.com/news/metabolon-verus-metabolomics-profiling-kit-now-available-to-order/): Metabolon, Inc\. announced today that the Metabolon Verus™ Metabolomics Profiling Kit is now available to order, moving Metabolon's first metabolomics kit from early access into full commercial availability\. - [Metabolon Completes Landmark Global Health Pilot Advancing Women's and Infant Health](https://www.metabolon.com/news/metabolon-completes-landmark-global-health-pilot-advancing-womens-and-infant-health/): Metabolon, Inc\. announces the successful completion of multiple pilot projects funded by the Gates Foundation aimed to identify metabolites strongly associated with clinical outcomes for diseases and conditions that disproportionately affect women and infants in low\- and middle\-income countries\. - [Metabolon Expands Integrated Bioinformatics Platform to Include Advanced Statistical Analysis Tool](https://www.metabolon.com/news/expands-integrated-bioinformatics-platform-advanced-statistical-analysis-tool/) - [Metabolon Launches New "Guide to Multiomics" and Accompanying Multiomics Webinar](https://www.metabolon.com/news/new-guide-to-multiomics-accompanying-multiomics-webinar/) ## Panels - [β\-Hydroxybutyrate \(BHB\) Single Analyte Assay](https://www.metabolon.com/services/targeted-metabolomics/beta-hydroxybutyrate/): BHB is a ketone body that is found in the blood\. This metabolite is relevant to diabetes, nutrition, neuroscience, and cardiovascular disease\. - [Salivary Glucose Single Analyte Assay](https://www.metabolon.com/services/targeted-metabolomics/salivary-glucose/): This assay verifies the accuracy of newly developed non\-invasive methods for self\-testing salivary glucose levels to manage diabetes\. - [Creatinine Single Analyte Assay](https://www.metabolon.com/services/targeted-metabolomics/creatinine/): Serum creatinine has been used as a biomarker for acute kidney injury and chronic kidney disease\. Urinary creatinine is used to test sample dilution\. - [C4 Single Analyte Assay](https://www.metabolon.com/services/targeted-metabolomics/c4/): Elevation of the metabolite, C4, characterizes bile acid malabsorption and other gastrointestinal pathologies\. - [Tryptophan/Kynurenine Ratio Targeted Panel](https://www.metabolon.com/services/targeted-metabolomics/tryptophan-kynurenine-ratio/) ## Categories - [Events](https://www.metabolon.com/category/events/) - [Blog](https://www.metabolon.com/category/blog/) - [Press](https://www.metabolon.com/category/press/) - [Capabilities](https://www.metabolon.com/category/blog/capabilities/) - [Omics](https://www.metabolon.com/category/blog/omics/) ## Tags - [Rare Disease](https://www.metabolon.com/tag/rare-disease/) - [Collaboration](https://www.metabolon.com/tag/collaboration/) - [Microbiome](https://www.metabolon.com/tag/microbiome/) - [Profile](https://www.metabolon.com/tag/profile/) ## Categories - [Project 7 Mega Menu](https://www.metabolon.com/layout_category/project-7-mega-menu/) - [Mega Menu](https://www.metabolon.com/layout_category/mega-menu/) - [Infographics](https://www.metabolon.com/layout_category/infographics/) ## Type - [section](https://www.metabolon.com/layout_type/section/) - [module](https://www.metabolon.com/layout_type/module/) - [layout](https://www.metabolon.com/layout_type/layout/) - [row](https://www.metabolon.com/layout_type/row/) ## Module Width - [regular](https://www.metabolon.com/module_width/regular/) ## Scope - [not\_global](https://www.metabolon.com/scope/not_global/) - [global](https://www.metabolon.com/scope/global/) ## Resource Categories - [Case Studies](https://www.metabolon.com/resources/type/case-studies/) - [Videos](https://www.metabolon.com/resources/type/videos/) - [eBooks](https://www.metabolon.com/resources/type/ebooks/) - [Live Webinars](https://www.metabolon.com/resources/type/live-webinars/) - [Posters](https://www.metabolon.com/resources/type/posters/) ## Topics - [Academia / Medical Research](https://www.metabolon.com/topic/academia-medical-research/) - [Biomarkers by Metabolon](https://www.metabolon.com/topic/biomarkers-by-metabolon/) - [Multiomics](https://www.metabolon.com/topic/multiomics/) - [Precision Medicine](https://www.metabolon.com/topic/precision-medicine/) - [Microbiome](https://www.metabolon.com/topic/microbiome/) ## Optional - [Sitemap index](https://www.metabolon.com/sitemap_index.xml)