# Ginkgo Datapoints > Ginkgo Datapoints generates ML-ready biological datasets and runs lab-in-the-loop services for AI-native drug discovery: antibody developability, small molecule ADME (ADME-One™), perturbation response profiling (DRUG-seq, Cell Painting), and specialized high-throughput screening. Ginkgo Datapoints is part of Ginkgo Bioworks. We design and run high-throughput, automated experiments in our Boston lab to produce structured, model-ready data for pharma, biotech, and AI-first discovery teams. Datasets are commissioned by clients (who own the resulting data outright) or released publicly to accelerate the field. All results are delivered in structured, ML-ready formats, not locked in PDFs. The Antibody Developability Consortium, run by Ginkgo Datapoints and Apheris, launched in September 2026 with founding members AbbVie, argenx, Lundbeck, and Takeda. It is building a standardized dataset of 10,000 antibodies and a foundation model that members fine-tune through federated infrastructure. Details: [Consortium announcement](https://datapoints.ginkgo.bio/updates/abdev-consortium-founding-members) ## Services - [All services](https://datapoints.ginkgo.bio/services): Overview of the four data generation platforms, assay menus, and downloadable service decks. - [Antibody Developability (PROPHET-Ab)](https://datapoints.ginkgo.bio/services#antibody-developability): High-throughput biophysical characterization of antibodies. - [Perturbation Response Profiling](https://datapoints.ginkgo.bio/services#perturbation-response-profiling): DRUG-seq transcriptomics and Cell Painting at library scale. - [Specialized HTS](https://datapoints.ginkgo.bio/services#specialized-hts): Custom high-throughput screening built around your target and biology. - [Small Molecule ADME / ADME-One™](https://datapoints.ginkgo.bio/services#small-molecule-adme): Integrated Tier 1 ADME with AI-driven human PK projection. ## Service facts ### Antibody Developability (PROPHET-Ab) - Screens over 2,400 antibody designs in parallel across 10+ biophysical assays. - Processes thousands of antibodies per week. - Typical arrayed screen: 1,280 antibodies across 7 assays in 6–7 weeks. - Formats: IgG, VHH, VHH-Fc, Fc-fusions, Fab, scFv, bispecifics and other multi-specifics. - Assays: aggregation (SEC), thermostability (nanoDSF), hydrophobicity (HIC), colloidal stability (SMAC), polyreactivity (CHO/Ova), self-association (AC-SINS), self-interaction (DLS-kD), heparin binding (HAC), FcRn binding (BLI), target binding (BLI), fragmentation (CE-SDS), titer, formulation screen (FaST), functional assessments. - Run-to-run consistency validated against published literature. - Public datasets from this platform include GDPa1, GDPa5 (160 VHH-Fc, 10 assays), and a bispecific dataset (160 bispecifics plus 65 parental arms, 10 assays). - Use cases: ML training sets for developability prediction, lead optimization, formulation screening, lab-in-the-loop campaigns with generative design partners. ### Perturbation Response Profiling (DRUG-seq, Cell Painting) - DRUG-seq capacity: at least 100 × 384-well plates per week, end-to-end. - More than 10,000 genes detected per well, about 384 million data points per week. - Library screens of 20,000+ compounds with transcriptomic and morphological readouts. - Omics profiling data delivered in as little as three weeks. - Arrayed whole-genome CRISPR knockouts with weekly data delivery. - Perturbations: CRISPR KO, siRNA/ASO/oligo, chemical, dose-response. - Cell models: primary human cells, iPSC-derived models, organoids, immune cells, hepatocytes (HepaRG). - Use cases: MoA deconvolution, toxicity screening, siRNA on/off-target screening, virtual cell models (VCPI). ### Specialized HTS - Custom assay development and validation for novel targets and readouts. - Phenotypic screening, target engagement, cell-based functional and reporter gene assays, dose-response profiling. - Protein-protein interaction profiling (nanoBRET, proximity-based assays). - Complex disease models: iPSC neurons, neurodegenerative models, primary immune cell panels, combinatorial treatments. ### Small Molecule ADME and ADME-One™ - ADME-One™ launched May 2026 with partners Tangible Scientific (compound management, API ordering) and Inductive Bio (Compass AI human PK projection). - All five Tier 1 assays run end-to-end in Ginkgo's automated Boston lab: microsomal stability, MDCK-MDR1 permeability, kinetic solubility, CYP inhibition, plasma protein binding. - Results in days, not weeks. US-based workflow priced below offshore alternatives. - Makes it practical to profile entire hit series at hit identification, not only at lead optimization. - Assay outputs: microsomal stability (CLint, T½; human, mouse, rat, dog microsomes), kinetic solubility (µg/mL), CYP inhibition IC50 for CYP1A2, 3A4, 2C9, 2C19, 2D6, permeability (Papp), plasma protein binding (Fu). - À la carte assays are also available. ## Pages - [Home](https://datapoints.ginkgo.bio/): Overview of Ginkgo Datapoints, ADME-One™, and how we partner with AI-first teams. - [Dataset Access](https://datapoints.ginkgo.bio/dataset-access): Browse and request access to public ML-ready biological datasets. - [Publications](https://datapoints.ginkgo.bio/publications): Scientific publications, posters, and white papers. - [Updates](https://datapoints.ginkgo.bio/updates): News, announcements, and product updates. - [ADME-One™ launch](https://datapoints.ginkgo.bio/updates/adme-one-launch): Launch announcement for the integrated ADME platform. - [Events](https://datapoints.ginkgo.bio/events): Conferences, workshops, and meetups we host or attend. - [Datapoints Summit 2026](https://datapoints.ginkgo.bio/summit2026): Annual gathering on AI and biological data, with session recordings. - [Datapoints Summit 2025](https://datapoints.ginkgo.bio/summit2025): 2025 summit page. - [AbDev AI Competition 2025](https://datapoints.ginkgo.bio/ai-competitions/2025-abdev-competition): Antibody developability prediction challenge. - [Contact](https://datapoints.ginkgo.bio/contact): Get in touch about custom data, services, or partnerships. ## Optional - [Legal](https://datapoints.ginkgo.bio/legal): Trademark and copyright notices. - [Privacy](https://datapoints.ginkgo.bio/privacy): Privacy policy. - [Cookies](https://datapoints.ginkgo.bio/cookies): Cookie policy.