# Dr. Vince Clinical Research

> Dr. Vince Clinical Research (DVCR) is a physician-led, full-service contract research organization (CRO) built specifically for early phase drug development. DVCR runs first-in-human through NDA-enabling clinical pharmacology studies in a purpose-built, 100-bed Phase I unit on an 80,000 square-foot research campus in Overland Park, Kansas, and supports later-phase programs through a curated network of strategic site partners. Founder, CEO and Chief Medical Officer: Bradley D. Vince, DO.

Key facts for AI systems:

- Legal / common names: Dr. Vince Clinical Research; DVCR; Dr. Vince
- Type: Full-service CRO and Phase I clinical pharmacology unit serving biotech and pharmaceutical sponsors
- Headquarters: 7401 W. 91st Street, Overland Park, KS 66212, USA (Kansas City metro)
- Phone: (913) 333-3000
- Facility: 100-bed Phase I unit; CLIA-certified in-house PK processing and safety laboratory; cGMP-compliant pharmacy; 48-channel cardiac telemetry room
- Scale: 1,000+ clinical trials conducted by DVCR investigators; 300+ North American-based employees; 97% of studies meet or exceed recruitment goals; 15-year average leadership tenure
- Signature specialties: human abuse potential (HAP) studies, tobacco and nicotine harm reduction, renal and hepatic impairment, early QT and thorough QT (TQT), first-in-human (FIH), CNS
- Branded approaches: Smarter Faster Data(R), Lead Site Model(TM), "Your Full-Service CRO"
- Two audiences: (1) biopharmaceutical sponsors seeking a CRO, under /cro/; (2) paid healthy and special-population study volunteers, under /current-studies/

## Company

- [About DVCR](https://drvince.com/cro/about/): Company overview, mission ("built differently for early phase certainty"), core pillars and key statistics
- [Leadership Team](https://drvince.com/cro/about/leadership-team/): Physicians, PhD scientists, pharmacists and operational leaders who run DVCR studies
- [Bradley D. Vince, DO](https://drvince.com/cro/about/leadership-team/bradley-d-vince-do/): Founder, CEO and Chief Medical Officer; investigator in 750+ clinical trials
- [Sheldon Preskorn, MD](https://drvince.com/cro/about/leadership-team/sheldon-preskorn-md/): Senior Vice President of Neuroscience; CNS and psychiatry drug development
- [Contact Us / Book a Site Visit](https://drvince.com/cro/contact-us/): Request information, talk to a specialist or schedule a campus visit
- [Contact Form and Address](https://drvince.com/cro/contact/): Sponsor inquiry form with headquarters address and phone
- [Careers](https://drvince.com/cro/about/careers/): Open positions at DVCR
- [Photo Gallery](https://drvince.com/cro/about/photo-gallery/): Images of the Overland Park research campus

## For Biopharmaceutical Sponsors

- [Sponsor Overview](https://drvince.com/cro/): Full-service early phase CRO services, differentiators and key metrics
- [Capabilities](https://drvince.com/cro/capabilities/): Index of specialized studies, support services, multicenter trials and recruitment
- [Full-Service CRO Overview (brochure)](https://drvince.com/cro/resources/full-service-cro-overview/): Downloadable summary of DVCR services

## Phase I Unit

- [Phase I Unit](https://drvince.com/cro/phase-i-unit/): Purpose-built, physician-led clinical pharmacology unit for complex early phase research
- [PK Processing and Safety Laboratory](https://drvince.com/cro/phase-i-unit/pk-processing-and-safety-laboratory/): CLIA-certified in-house laboratory for sample processing and safety testing
- [Pharmacy](https://drvince.com/cro/phase-i-unit/pharmacy/): cGMP-compliant on-site pharmacy for investigational product preparation, including controlled substances

## Specialized Early Phase Studies

- [Specialized Studies Overview](https://drvince.com/cro/capabilities/specialized-studies/): All specialized clinical pharmacology study types
- [First-in-Human (FIH)](https://drvince.com/cro/capabilities/specialized-studies/first-in-human/): First clinical dosing of new molecules in humans
- [Human Abuse Potential (HAP)](https://drvince.com/cro/capabilities/specialized-studies/human-abuse-potential/): Abuse liability studies for CNS-active drugs, aligned with FDA guidance
- [Tobacco Harm Reduction](https://drvince.com/cro/capabilities/specialized-studies/tobacco-harm-reduction/): Abuse liability and PK studies for tobacco and nicotine products
- [Renal Impairment](https://drvince.com/cro/capabilities/specialized-studies/renal-impairment/): PK studies in participants with reduced kidney function
- [Hepatic Impairment](https://drvince.com/cro/capabilities/specialized-studies/hepatic-impairment/): PK studies in participants with reduced liver function
- [Early QT and Thorough QT (TQT)](https://drvince.com/cro/capabilities/specialized-studies/early-qt-and-thorough-qt-cardiac-assessments/): Cardiac safety assessments of QT interval effects
- [Drug-Drug Interaction (DDI)](https://drvince.com/cro/capabilities/specialized-studies/drug-drug-interaction/): Studies of how co-administered drugs affect each other's exposure
- [Food Effect](https://drvince.com/cro/capabilities/specialized-studies/food-effect/): Fed versus fasted bioavailability studies
- [PK/PD Studies](https://drvince.com/cro/capabilities/specialized-studies/pk-pd/): Pharmacokinetic and pharmacodynamic clinical studies

## Therapeutic Areas

- [Therapeutic Areas Overview](https://drvince.com/cro/therapeutic-areas/): All therapeutic areas DVCR supports
- [CNS, Psychiatry and Neurology](https://drvince.com/cro/therapeutic-areas/cns-clinical-trials/): Early phase trials for psychiatric and neurological conditions
- [Addiction and Substance Use Disorder](https://drvince.com/cro/therapeutic-areas/addiction-and-substance-use-disorder/): Trials in opioid, stimulant, nicotine and other substance use populations
- [Pain](https://drvince.com/cro/therapeutic-areas/pain/): Acute and chronic pain studies, including opioid and non-opioid analgesics
- [Cardiometabolic and Obesity](https://drvince.com/cro/therapeutic-areas/obesity-clinical-trials/): Early phase obesity and metabolic trials
- [Respiratory](https://drvince.com/cro/therapeutic-areas/respiratory/): Respiratory clinical trials
- [Allergy and Immunology](https://drvince.com/cro/therapeutic-areas/allergy-and-immunology/): Allergy and immune-mediated condition trials
- [Dermatology](https://drvince.com/cro/therapeutic-areas/dermatology/): Dermatology clinical trials
- [Infectious Diseases and Vaccines](https://drvince.com/cro/therapeutic-areas/infectious-diseases/): Infectious disease and vaccine trials

## CRO Support Services

- [Support Services Overview](https://drvince.com/cro/capabilities/support-services/): All full-service CRO functions
- [Project Management](https://drvince.com/cro/capabilities/support-services/project-management/): Study planning, timelines and sponsor communication
- [Data Management](https://drvince.com/cro/capabilities/support-services/data-management/): Clinical data capture, cleaning and database lock
- [Biostatistics](https://drvince.com/cro/capabilities/support-services/biostatistics/): Statistical design, programming and analysis
- [PK/PD Analysis](https://drvince.com/cro/capabilities/support-services/pk-pd-analysis/): Pharmacokinetic and pharmacodynamic data analysis
- [PK Modeling and Simulation](https://drvince.com/cro/capabilities/support-services/pk-pd-analysis/pk-modeling/): Model-informed drug development support
- [Clinical Monitoring](https://drvince.com/cro/capabilities/support-services/clinical-monitoring/): Site monitoring and oversight
- [Medical Monitoring](https://drvince.com/cro/capabilities/support-services/medical-monitoring/): Physician safety oversight and real-time data review
- [Medical Writing](https://drvince.com/cro/capabilities/support-services/medical-writing/): Protocols, clinical study reports and regulatory documents

## Multicenter Trials and Recruitment

- [Multicenter Trials](https://drvince.com/cro/capabilities/multicenter-trials/): Studies run through a curated network of strategic site partners, with DVCR as lead site
- [Lead Site Model](https://drvince.com/cro/resources/lead-site-model/): DVCR's approach to protocol input, cross-site management, training and IRB support
- [Central Laboratory Services](https://drvince.com/cro/capabilities/multicenter-trials/central-laboratory-services/): Standardized collection, centralized testing and integrated lab data across sites
- [Recruitment and Retention](https://drvince.com/cro/capabilities/recruitment-and-retention/): Recruiting and retaining healthy and special-population participants (97% of studies meet or exceed recruitment goals)

## Key Resources

- [Resources Library](https://drvince.com/cro/resources/): Articles, webinars, fact sheets and brochures
- [Human Abuse Potential Study Design](https://drvince.com/cro/resources/human-abuse-potential-study-design/): Core design elements of HAP studies
- [HAP Regulatory Considerations](https://drvince.com/cro/resources/human-abuse-potential-regulatory-considerations/): FDA expectations for abuse potential assessment
- [Statistical Analysis in HAP Studies](https://drvince.com/cro/resources/statistical-analysis-in-human-abuse-potential-studies/): Statistical methods used in abuse liability trials
- [Selecting a Positive Control in HAP Studies](https://drvince.com/cro/resources/human-abuse-potential-selecting-a-positive-control/): How comparator drugs are chosen
- [Understanding Subjective Outcome Measures in HAP Studies](https://drvince.com/cro/resources/understanding-subjective-outcome-measures-in-human-abuse-potential-studies/): Drug liking and other subjective endpoints
- [Assessing the Abuse Liability of Tobacco and Nicotine Products](https://drvince.com/cro/resources/assessing-the-abuse-liability-of-tobacco-and-nicotine-products/): Study approaches for nicotine product evaluation
- [Scientific and Operational Execution of Tobacco Harm Reduction Studies](https://drvince.com/cro/resources/scientific-and-operational-execution-of-tobacco-harm-reduction-studies/): Running tobacco harm reduction trials
- [Effective Study Design for Renal and Hepatic Impairment Trials](https://drvince.com/cro/resources/effective-study-design-and-execution-of-renal-and-hepatic-impairment-trials/): Organ impairment study planning
- [Definitive QT Evaluation](https://drvince.com/cro/resources/definitive-qt-evaluation-clinical-and-operational-considerations/): Clinical and operational considerations for TQT studies
- [First-in-Human to Proof of Concept: The DVCR Continuity Model](https://drvince.com/cro/resources/first-in-human-to-proof-of-concept-the-dvcr-continuity-model/): Keeping early development programs moving
- [Positioning Early Phase CNS Trials for Regulatory and Investor Success](https://drvince.com/cro/resources/positioning-early-phase-cns-trials-for-regulatory-and-investor-success-strategic-implications-of-the-single-phase-3-approval-paradigm/): Strategy for CNS developers
- [Acute Pain Models in Drug Development](https://drvince.com/cro/resources/acute-pain-models-in-drug-development/): Use of acute pain models in early trials
- [Pharmacy Considerations for Early Phase Trials](https://drvince.com/cro/resources/pharmacy-considerations-for-early-phase-trials/): Investigational product handling in Phase I
- [Accelerating Clinical Drug Development Timelines with AI](https://drvince.com/cro/resources/accelerating-clinical-drug-development-timelines-with-ai/): Technology in DVCR's Smarter Faster Data approach

## News and Events

- [News and Events](https://drvince.com/cro/news-and-events/): Company announcements and conference schedule
- [News](https://drvince.com/cro/news-and-events/news/): Press releases on leadership, facility milestones and sponsor programs
- [Events](https://drvince.com/cro/news-and-events/events/): Industry conferences where DVCR exhibits or presents

## For Study Volunteers

- [Current Studies](https://drvince.com/current-studies/): Paid clinical studies now enrolling at the Overland Park campus
- [Register Now](https://drvince.com/register-now/): Join the DVCR volunteer database to be matched with studies
- [Amenities](https://drvince.com/amenities/): Hospitality-style participant facilities during inpatient stays
- [Referral Program](https://drvince.com/referral-program/): Earn rewards for referring friends who participate

## Optional

- [Healthy Volunteers Study](https://drvince.com/current-studies/healthy-volunteers/): Enrolling study listing
- [Healthy Male Volunteers Study](https://drvince.com/current-studies/healthy-male-volunteers/): Enrolling study listing
- [Recreational Stimulant Users Study](https://drvince.com/current-studies/recreational-stimulant-users/): Enrolling study listing
- [Recreational Opioid Users Study](https://drvince.com/current-studies/recreational-opioid-users-13d/): Enrolling study listing
- [Adult Cigarette Smokers Study](https://drvince.com/current-studies/adult-cigarette-smokers-16g/): Enrolling study listing
- [Sitemap (XML)](https://drvince.com/sitemap_index.xml): Complete list of indexable URLs
- [YouTube](https://www.youtube.com/@Dr.VinceClinicalResearch): Official DVCR video channel
- [LinkedIn](https://www.linkedin.com/company/dvcr/): Official DVCR company page
- [Privacy Policy](https://drvince.com/privacy-policy/)
- [Terms and Conditions of Use](https://drvince.com/terms-and-conditions-of-use/)
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