# BMKGENE - Multi-omics Sequencing Services > BMK has been actively engaged in innovation and development of high-throughput sequencing technologies and bioinformatics for over 15 years. ### Company Beijing Biomarker Technologies Co., LTD. ### Description Biomarker Technologies(BMKGENE) is an industry-leading genomics service provider, headquartered in Beijing. It has been actively engaged in innovation and developing high-throughput sequencing technologies and bioinformatics for over 16 years. With a passionate and highly-skilled R&D team , BMKGENE is committed to providing the most comprehensive sequencing services covering genomics, transcriptomics, single-cell omics and epigenetics. ### Address Room 605A, 6th floor, Building 1, Yard 9, Nanfaxin Section, Shunping Road, Nanfaxin Town, Shunyi District, Beijing ### Phone 00852-22086076 ### Mobile 0086-400-600-3186 ### Email tech@bmkcloud.com ### Fax 010-57045001 ## Home [Home](https://www.bmkgene.com/) ## index [index](https://www.bmkgene.com/index/):index ## Online Event 11 [Online Event 11](https://www.bmkgene.com/online-event-11/):15min webinar series how much RNA is really needed for RNA seq This webina provided a comprehensive overview of mRNA sequencing (mRNA-seq), exploring ## An introduction to the BMKMANU S3000 chip & spatial transcriptomics at the subcellular level [An introduction to the BMKMANU S3000 chip & spatial transcriptomics at the subcellular level](https://www.bmkgene.com/an-introduction-to-the-bmkmanu-s3000-chip-spatial-transcriptomics-at-the-subcellular-level/): Spatial organization of cells plays a vital role in various biological processes, such as immune infiltration, embryo development, etc. Spatial tr ## Class 5|visualizing key pathways and WGCNA with real data [Class 5|visualizing key pathways and WGCNA with real data](https://www.bmkgene.com/class-5visualizing-key-pathways-and-wgcna-with-real-data/): Class 5|visualizing key pathways and WGCNA with real data In this session, we explored advanced techniques for enhancing image presenta ## Online Events [Online Events](https://www.bmkgene.com/online-events/): In this webinar, we'll guide you through the entire workflow of a spatial transcriptomics study—from sample collection o data ## online event 10 [online event 10](https://www.bmkgene.com/online-event-10/):online event 10 ## Class 4 Advanced Filtering and Dynamic Reporting with BMKCloud [Class 4 Advanced Filtering and Dynamic Reporting with BMKCloud](https://www.bmkgene.com/online-video4/):This presentation delves into evaluating outlier samples, analyzing clustering patterns, adjusting differential analysis parameters, and updating rep ## Class 3 From Gene to Visualization Basic and Advanced Drawings [Class 3 From Gene to Visualization Basic and Advanced Drawings](https://www.bmkgene.com/online-video3/):This presentation covers three main topics to help you make the most of our cloud platform's capabilities:1. One-step Drawing: Discover the simplicit ## Class 2 In-depth Result Filtering Composite Multiple Criteria [Class 2 In-depth Result Filtering Composite Multiple Criteria](https://www.bmkgene.com/online-video2/):In this presentation, you will learn:1. Differential Gene Selection: Five Methods2. Visualization Post-Filtering: Using Heatmap as an Example + Advanc ## Class 1 From data to report A guide to RNAseq (reference) Usage [Class 1 From data to report A guide to RNAseq (reference) Usage](https://www.bmkgene.com/online-video1/):In this presentation, you will learn:1. Course Overview2. Cloud Platform Data Management Approach3. How to Submit Analysis Tasks: On a Case of RNA-seq ## BI online lessons [BI online lessons](https://www.bmkgene.com/bi-online-lessons/): BMKCloud is an easy-to-use bioinformatics platform that enables researchers to rapidly analyze high-throughput sequencing data and gain biological in ## How to submit task on BMKCloud? [How to submit task on BMKCloud?](https://www.bmkgene.com/how-to-submit-task-on-bmkcloud/): You can also submit the task via the steps below:1. Log in to your BMKCloud account2. Click Bioinformatics > APPs > mRNA (Reference) > Op ## How to download report on BMKCloud [How to download report on BMKCloud ](https://www.bmkgene.com/how-to-download-report-on-bmkcloud/): You can also download your report via the steps below:1.Open the home page of BMKCloud, navigate to project-project2.Click on your report to view ## Manual and Guideline [Manual and Guideline](https://www.bmkgene.com/manual-and-guideline/): BMKCloud is an easy-to-use bioinformatics platform that enables researchers to rapidly analyze high-throughput sequencing data and gain biological ## Online Event 9 [Online Event 9](https://www.bmkgene.com/online-event-9/): Genome de novo assembly involves reconstructing an organism's genome through sequencing and DNA analysis. High-quality reference genomes are the ba ## Online Event 8 [ Online Event 8](https://www.bmkgene.com/online-event-8/): High-throughput sequencing studies of microbial communities have become widespread and have significantly advanced our understanding of human, env ## BMKGENE Upcoming Webinar [BMKGENE Upcoming Webinar](https://www.bmkgene.com/bmkgene-upcoming-webinar/): Spatial organization of cells plays vital role in virtually all biological areas, such as neuroscience, oncology, developmental biology, immunology, ## Evolutionary Genetics [Evolutionary Genetics ](https://www.bmkgene.com/evolutionary-genetics/): Evolutionary Genetics Evolutionary genetic studies aim to understand the evolutionary trajectory of populations using polymorphism informati ## WGS (Nanopore) [WGS (Nanopore)](https://www.bmkgene.com/wgs-nanopore/): WGS (Nanopore) Whole genome re-sequencing with Nanopore is a popular method for identifying genomic variants, particularly structural varian ## mRNA-seq (NGS) - De novo [mRNA-seq (NGS) - De novo](https://www.bmkgene.com/mrna-seq-ngs-de-novo/): mRNA-seq (NGS) - De novo   mRNA sequencing allows profiling of all mRNA transcripts in cells under specific conditions and is a widely ## PacBio 2+3 Full-Length mRNA Solution [PacBio 2+3 Full-Length mRNA Solution](https://www.bmkgene.com/pacbio-23-full-length-mrna-solution/): PacBio 2+3 Full-Length mRNA Solution While NGS-based mRNA sequencing serves as a versatile tool for gene expression quantification, its reli ## Nanopore Full-length transcriptome [Nanopore Full-length transcriptome](https://www.bmkgene.com/nanopore-full-length-transcriptomics/): Nanopore Full-Length Transcriptomics Complex and variable alternative isoforms in organisms are important genetic mechanisms for regulating gene e ## Pacbio Full-length transcriptome [Pacbio Full-length transcriptome](https://www.bmkgene.com/pacbio-full-length-transcriptome-non-reference/): Pacbio Full-length transcriptome PacBio Full-Length Transcriptome Sequencing, Isoseq, enables accurate identification of transcript isoforms ## WGS (NGS) [WGS (NGS)](https://www.bmkgene.com/ngs-wgs-illuminabgi/): WGS (NGS) Whole genome re-sequencing with Illumina or DNBSEQ is a popular method for identifying genomic variants, including single nucleoti ## GWAS [GWAS](https://www.bmkgene.com/gwas/): GWAS Genome-wide association study (GWAS) aims to identify loci associated with specific traits or phenotypes, often of economic or human he ## CircRNA [CircRNA](https://www.bmkgene.com/circ-rna/): CircRNA   Circular RNAs (circRNAs) are non-coding RNAs that form circular structures and have multiple regulatory roles, including comp ## lncrna [lncrna](https://www.bmkgene.com/lncrna/): lncRNA Long non-coding RNAs (lncRNA) are RNAs longer than 200 nucleotides with low coding potential but with critical regulatory functions. ## Online Event 7 [ Online Event 7](https://www.bmkgene.com/online-event-7/): How to Easier Start Your Analysis with Transcriptome Sequencing Data?                  Moving from Multiple Bioinformatics Tools or ## Online Event 6 [Online Event 6](https://www.bmkgene.com/online-event-6/): 1. NGS-based mRNA Sequencing In this session, we will briefly go through the basic principle, workflow and analysis in NGS-based mRNA sequencing 2 ## Online Event 5 [Online Event 5](https://www.bmkgene.com/online-event-5/): Performance of Different Sequencing Technologies in Resolving Metagenomics. In this lecture, She gives an introduction on the applications of d ## Bmk_Space_Mapping.R Operating Manual [Bmk_Space_Mapping.R Operating Manual](https://www.bmkgene.com/bmk_space_mapping-r-operating-manual/): 1, Open the script file source(‘xxx’) #’xxx’ script path, for example ’C:/Users/R/Desktop/qq.R’ 2, Creat Seurat object and ## Small RNA [Small RNA](https://www.bmkgene.com/small-rna/): Small RNA  Small RNAs are short non-coding RNAs with an average length of 18-30 nt, including miRNA, siRNA and piRNA, which play important ## Metagenomics (NGS) [Metagenomics (NGS)](https://www.bmkgene.com/metagenomics-ngs/): Metagenomics (NGS)   Shotgun metagenomics with Illumina is a popular tool for studying microbiomes by directly sequencing DNA from comp ## Amplicon Sequencing(16S/18S/ITS) [Amplicon Sequencing(16S/18S/ITS)](https://www.bmkgene.com/amplicon-sequencing16s18sits/): Amplicon Sequencing(16S/18S/ITS)   Amplicon (16S/18S/ITS) sequencing with Illumina is a method of analyzing microbial diversity by iden ## mRNA-seq (NGS) with reference genome [mRNA-seq (NGS) with reference genome](https://www.bmkgene.com/ngs-mrnareference/): mRNA-seq (NGS) with reference genome RNA-seq is a standard tool across life and crop sciences, bridging the gap between genomes and proteome ## Online Event 4 [Online Event 4](https://www.bmkgene.com/online-event-4/): SLAF-seq, a high-effective and accurate way to detect variants and develop biomarkers. A quick overview of SLAF from principle to material selecti ## Powerful Analysis Tools [Powerful Analysis Tools](https://www.bmkgene.com/powerful-analysis-tools/): Heatmap Matrix data file is used for heat map drawing, which can filter, normalize and cluster matrix data. It is mostly used for cluster analysis of ## Flexible Analysis APPs [Flexible Analysis APPs](https://www.bmkgene.com/flexible-analysis-apps/): This pipeline uses NGS RNA-Seq data as input and produces results from multiple downstream analyses including but not limited to: sequencing data ## BMKCloud Bioinformatics Analysis Platform [BMKCloud Bioinformatics Analysis Platform](https://www.bmkgene.com/bmkcloud-bioinformatics-analysis-platform/): BMKCloud is an easy-to-use bioinformatics platform that enables researchers to rapidly analyze high-throughput sequencing data and gain biological in ## Software Downloads [Software Downloads](https://www.bmkgene.com/software-downloads/):Software Downloads ## Online Event 3 [Online Event 3](https://www.bmkgene.com/online-event-3/): Spatial organization of cells plays vital role in various biological processes, such as immune infiltration, embryo development, etc. Spatial tran ## Online Event 2 [Online Event 2](https://www.bmkgene.com/online-event-2/): High Accuracy Long Read from PacBio are transforming sequencing. HiFi reads generate superior results for a range of applications: acquisition of ## New Product Launch - BMKMANU S1000, Sub-cellular Level Spatial Transcriptomics - Buy Four Get One Free! [New Product Launch - BMKMANU S1000, Sub-cellular Level Spatial Transcriptomics - Buy Four Get One Free!](https://www.bmkgene.com/new-product-launch-bmkmanu-s1000-sub-cellular-level-spatial-transcriptomics-buy-four-get-one-free/): Exploring gene expression patterns at the original location of an organism is crucial for understanding the types and functions of its cells. Howev ## Experience the Power of PacBio Revio with BMKGENE! Higher throughput! Lower cost! Special Offer! [Experience the Power of PacBio Revio with BMKGENE! Higher throughput! Lower cost! Special Offer!](https://www.bmkgene.com/experience-the-power-of-pacbio-revio-with-bmkgene-higher-throughput-lower-cost-special-offer/): BMKGENE is proud to announce the availability of PacBio's advanced sequencer, Revio, which helps us deliver higher throughput and higher quality lon ## BMKGENE Anniversary| Special Offer on One-Stop De novo Genome [BMKGENE Anniversary| Special Offer on One-Stop De novo Genome](https://www.bmkgene.com/bmkgene-anniversary-special-offer-on-one-stop-de-novo-genome-assembly/):A wonderful first year of BMKGENE's global business！BMKGENE is having a time-limited discount on the De Novo Genome Assembly to assist with plant a ## Time to Plan for Your First Sub-cellular Level Spatial Transcriptome [Time to Plan for Your First Sub-cellular Level Spatial Transcriptome](https://www.bmkgene.com/time-to-plan-for-your-first-sub-cellular-level-spatial-transcriptome-study/):On the 1st Anniversary of BMKGENE, BMKGENE is delighted to offer a time-limited discount on spatial transcriptome service with “Try First, Pay Late ## Sample Preparation Guidelines [Sample Preparation Guidelines](https://www.bmkgene.com/sample-preparation-guidelines/): ## Online Event [Online Event](https://www.bmkgene.com/online-event/): The aim of the webinar is to provide participants with essential knowledge and practical guidance on the fundamental aspects of transcriptome sequ ## Webinars [Webinars](https://www.bmkgene.com/webinars/):Our Webinars ## Resource [Resource](https://www.bmkgene.com/resource/):Resource ## Product Flyer and Brochure [Product Flyer and Brochure](https://www.bmkgene.com/product-flyer-and-brochure/):Genome Sequencing Human Whole Genome Sequencing and Whole Exome Sequencing--BMKGENE-2023.02 Plant and Animal Whole Genome Re-sequencing--BMKGENE ## Privacy Policy [Privacy Policy](https://www.bmkgene.com/privacy-policy/):PRIVACY STATEMENT This notice was last updated on March 28, 2022 This Privacy Statement (“Statement”) serves to describe how we, Biomarker Techno ## About Us [About Us](https://www.bmkgene.com/about-us/): Biomarker Technologies (BMK) Biomarker Technologies(BMKGENE), as one of the leading provider of genomics services, is founded in 2009, headquarte ## Enterprise Qualification [Enterprise Qualification](https://www.bmkgene.com/enterprise-qualification/):Enterprise Qualification ## Our History [Our History ](https://www.bmkgene.com/our-history/):Our History ## FAQs [FAQs](https://www.bmkgene.com/faqs/): FAQ FREQUENTLY ASKED QUESTIONS What are your prices? Our prices are subject to change depending on supply and other market factors. We wi ## Factory Tour [Factory Tour](https://www.bmkgene.com/factory-tour/): Fully Automated Platform for Next-generation sequencing--Brilliant Lab 1000 Biomarker technologies (BMKGENE) and PerkinElmer have jointly built a ful ## Contact Us [Contact Us](https://www.bmkgene.com/contact-us/): Locations GERMANY Biomarker Technologies (BMK) GmbH Email: info@bmkgene.com Tel : +49 (0) 25153893975 Address: BioZ, Johann-Krane-Weg 42, 481 ## BMKCloud [BMKCloud](https://www.bmkgene.com/products/bmkcloud/) ## Epigenetics [Epigenetics](https://www.bmkgene.com/products/epigenetics/) ## Extraction Kits of S16 Nucleic Acid Extractor [Extraction Kits of S16 Nucleic Acid Extractor](https://www.bmkgene.com/products/extraction-kits-of-s16-nucleic-acid-extractor/) ## Featured [Featured](https://www.bmkgene.com/featured/) ## Genome Sequencing [Genome Sequencing](https://www.bmkgene.com/products/genomics/) ## hidden [hidden](https://www.bmkgene.com/hidden/) ## Microbiomics [Microbiomics](https://www.bmkgene.com/products/microbiomics/) ## Product [Product](https://www.bmkgene.com/product/) ## Products [Products](https://www.bmkgene.com/products/) ## Sequencing Only [Sequencing Only](https://www.bmkgene.com/products/sequencing/) ## Single-Cell Omics [Single-Cell Omics](https://www.bmkgene.com/products/single-cell-omics/) ## Transcriptomics [Transcriptomics](https://www.bmkgene.com/products/transcriptomics/) ## Full-length mRNA sequencing -PacBio [Full-length mRNA sequencing -PacBio](https://www.bmkgene.com/de-novo-full-length-transcriptome-sequencing-pacbio-product/):Features ● cDNA synthesis from poly-A mRNA followed by library preparation ● Sequencing in CCS mode, generating HiFi reads ● Sequencing of th ## Bulked Segregant analysis [Bulked Segregant analysis](https://www.bmkgene.com/bulked-segregant-analysis-product/):Service Advantages Service Specifications Bioinformatics analyses ● Whole genome resequencing   ● Data processing   ● SNP/Indel calling   ## DNA/RNA sequencing -PacBio Sequencer [DNA/RNA sequencing -PacBio Sequencer](https://www.bmkgene.com/dna-sequencing-pacbio-sequencer-product/):Features Two sequencing modes on PacBio sequencer: Continuous Long Read (CLR) and Circular Consensus Read (CCS) Sequencing Mode Library Size Theor ## Comparative Genomics [Comparative Genomics](https://www.bmkgene.com/comparative-genomics-product/):Service Advantages Service Specifications Bioinformatics analyses ● Gene family ● Phylogenetics ● Divergence time ● Selective pressure ● ## Evolutionary Genetics [Evolutionary Genetics](https://www.bmkgene.com/evolutionary-genetics-product/):Service Advantages Service Specifications and requirements Sample Requirements and Delivery Sample Requirements:   Species  Tissue  WGS ## Hi-C Based Genome Assembly [Hi-C Based Genome Assembly ](https://www.bmkgene.com/hi-c-based-genome-assembly-product/):Service Features ● Sequencing on Illumina NovaSeq with PE150. ● Service requires tissue samples, instead of extracted nucleic acids, to cross-li ## Plant/Animal De Novo Genome Sequencing [Plant/Animal De Novo Genome Sequencing](https://www.bmkgene.com/plantanimal-de-novo-genome-sequencing-product/):Service Features ● Integration of multiple sequencing and bioinformatic services in a one-stop solution:                  Genome survey wi ## CircRNA Sequencing-Illumina [CircRNA Sequencing-Illumina](https://www.bmkgene.com/circrna-sequencing-illumina-product/):Bioinformatics Data QC Genome alignment CircRNA identification CircRNA expression Differential expression analysis   ## Long Non-coding Sequencing-Illumina [Long Non-coding Sequencing-Illumina](https://www.bmkgene.com/long-non-coding-sequencing-illumina-product/):Service Advantages Sample Requirements and Delivery ● Plants:   Root, Stem or Petal: 450 mg   Leaf or Seed: 300 mg   Fruit: 1.2 g ● Animal:  ## Non-Reference based mRNA Sequencing-NGS [Non-Reference based mRNA Sequencing-NGS](https://www.bmkgene.com/non-reference-based-mrna-sequencing-illumina-product/): Features Service Advantages Sample Requirements and Delivery Library Sequencing strategy Data recommended Quality Control ## Small RNA Sequencing-Illumina [Small RNA Sequencing-Illumina](https://www.bmkgene.com/small-rna-sequencing-illumina-product/):Features ● Library preparation includes a size selection step ● Bioinformatic analysis centered around miRNA prediction and their targets Servic ## Whole Transcriptome Sequencing - Illumina [Whole Transcriptome Sequencing - Illumina](https://www.bmkgene.com/whole-transcriptome-sequencing-illumina-product/):Bioinformatics On top of all the analysis on each different, the 4 types of RNA are combined into our joint analysis:  Co-expression analysis betwe ## PacBio-Full-length 16S/18S/ITS Amplicon Sequencing [PacBio-Full-length 16S/18S/ITS Amplicon Sequencing](https://www.bmkgene.com/pacbio-full-length-transcriptome-non-reference-product/):Raw data procession CCS extraction Full-length non-chimeric(FLNC) reads identification Consensus transcripts identification Transcipt identifica ## 16S/18S/ITS Amplicon Sequencing-NGS [16S/18S/ITS Amplicon Sequencing-NGS](https://www.bmkgene.com/16s18sits-amplicon-sequencing-ngs-product/): Service Features ●  Sequencing platform: Illumina NovaSeq. ●  Amplification of short regions of 16S, 18S and ITS, among other amplificatio ## 16S/18S/ITS Amplicon Sequencing-PacBio [16S/18S/ITS Amplicon Sequencing-PacBio](https://www.bmkgene.com/16s18sits-amplicon-sequencing-pacbio-product/): Service Features ●  Sequencing platform: PacBio Revio ●  Sequencing mode: CCS (HiFi reads) ●  Amplification of target region followed ## Metagenomic Sequencing -NGS [Metagenomic Sequencing -NGS](https://www.bmkgene.com/metagenomic-sequencing-product/): Service Advantages Service Specifications Service Work Flow Sample delivery Library construction Sequencing ## Metagenomic Sequencing-TGS [Metagenomic Sequencing-TGS](https://www.bmkgene.com/nanopore-based-metagenome-sequencing-product/):Service Features Service Advantages Service Specifications Sample Requirements   Concentration (ng/µL) Total amount (µg) Volume (µL) I ## Metabolomics [Metabolomics](https://www.bmkgene.com/metabolomics-product/):Sample Requirements Non-targeted metabolomics Sample types Recommended sample amount Biological Repetition LC-MS/GC-MS untargeted metab ## Proteomics [Proteomics](https://www.bmkgene.com/proteomics-product/):Service Specifications Sample Requirements Service Work Flow ## Amplicon (16S/18S/ITS) [Amplicon (16S/18S/ITS)](https://www.bmkgene.com/amplicon-16s18sits-product/):Data Processing Raw data quality control Operational Taxonomic Unit(OTU) Clustering Taxonomy Species annotation Phylogenetic tree Components ## BSA [BSA](https://www.bmkgene.com/bsa-product/): Bioinformatics Raw data quality control Reference genome alignment Tag clustering (non-ref) SNP and InDe ## circ-RNA [circ-RNA](https://www.bmkgene.com/circ-rna-product/): Bioinformatics Raw data quality control Reference genome alignment CircRNA identification circRNA locus ## Evolutionary Genetics [Evolutionary Genetics](https://www.bmkgene.com/evolutionary-genetics-2-product/):Evolutionary Genetics ## Nanopore Full-length transcriptomics [Nanopore Full-length transcriptomics](https://www.bmkgene.com/nanopore-full-length-transcriptomics-product/): Bioinformatics Raw data quality control Full-length transcript assessment Transcript de-redundance Gene ## GWAS [GWAS](https://www.bmkgene.com/gwas-product/): Bioinformatics Raw data quality control Alignment against reference genome Genome-wide variation identification ## LncRNA [LncRNA](https://www.bmkgene.com/lncrna-product/):Bioinformatics Raw data quality control Alignment with reference genome Transcript assembly Correlation analysis Known lncRNA identification ## Metagenomics (NGS) [Metagenomics (NGS)](https://www.bmkgene.com/metagenomics-ngs-product/):Transcipt identification Raw data processing Metagenome assembly Metagenome component analysis PCA Function annotation Alpha diversity anal ## mRNA(Reference) [mRNA(Reference)](https://www.bmkgene.com/mrnareference-product/):mRNA(Reference) ## NGS-WGS (Illumina/BGI) [NGS-WGS (Illumina/BGI)](https://www.bmkgene.com/ngs-wgs-illuminabgi-product/): ## small RNA [small RNA](https://www.bmkgene.com/small-rna-product/): Bioinformatics Raw data quality control Common and unique sequence among samples Small RNA classification ## De novo Bacterial Genome Assembly [De novo Bacterial Genome Assembly](https://www.bmkgene.com/bacteria-complete-genome-product/): Service Features ●  With two possible options to choose from depending on the desired degree of genome completeness. ●  Draft Genome Opt ## Toolkits [Toolkits](https://www.bmkgene.com/toolkits-product/): Heatmap Drawer   Heatmap drawer is used for heat map drawing, which can filter, normalize and cluster matrix data.It is mostly used for cl ## De novo Fungal Genome Assembly [De novo Fungal Genome Assembly](https://www.bmkgene.com/fungal-genome-product/): Service Features With three possible options to choose from depending on the desired degree of genome completeness: ●   Draft Genome Option: ## Metatranscriptome Sequencing [Metatranscriptome Sequencing](https://www.bmkgene.com/metatranscriptome-sequencing-product/): Service Features ● rRNA depletion followed by directional mRNA library preparation. ● Sequencing on Illumina NovaSeq. Service Advantage ## Bacterial and Fungal Whole Genome Re-Sequencing [Bacterial and Fungal Whole Genome Re-Sequencing](https://www.bmkgene.com/bacterial-and-fungal-whole-genome-re-sequencing-product/): Service Advantages ● Bioinformatic Analysis Includes Variant Calling: Providing functional insights into the re-sequenced genomes. ● Exten ## Assay for Transposase-Accessible Chromatin with High Throughput Sequencing (ATAC-seq) [Assay for Transposase-Accessible Chromatin with High Throughput Sequencing (ATAC-seq)](https://www.bmkgene.com/assay-for-transposase-accessible-chromatin-with-high-throughput-sequencing-atac-seq-product/): Service Features Service Advantages Service Specifications Sample Requirements Samples type: Tissues, live or frozen cells, blood â ## Chromatin Immunoprecipitation Sequencing (ChIP-seq) [Chromatin Immunoprecipitation Sequencing (ChIP-seq)](https://www.bmkgene.com/chromatin-immunoprecipitation-equencing-product/): Service Advantages Service Specifications Sample Requirements Total amount: ≥10 ng Fragment size distribution: 100-750 bps Service ## Full-Length mRNA Sequencing-Nanopore [Full-Length mRNA Sequencing-Nanopore](https://www.bmkgene.com/full-length-mrna-sequencing-nanopore-product/):Features ●  Capture of poly-A mRNA followed by cDNA synthesis and library preparation ●  Sequencing of the full-length transcripts ●  Bioinfo ## Prokaryotic RNA Sequencing [Prokaryotic RNA Sequencing](https://www.bmkgene.com/prokaryotic-rna-sequencing-product/):RNA sequencing empowers the comprehensive profiling of all RNA transcripts within cells under specific conditions. This cutting-edge technology serves ## Eukaryotic mRNA Sequencing-NGS [Eukaryotic mRNA Sequencing-NGS](https://www.bmkgene.com/eukaryotic-mrna-sequencing-illumina-product/): Features Advantages Sample Requirements and Delivery Library Sequencing strategy Data recommended Quality Control Poly A enric ## Whole genome bisulfite sequencing(WGBS) [Whole genome bisulfite sequencing(WGBS)](https://www.bmkgene.com/whole-genome-bisul%ef%ac%81te-sequencing-product/):Service Features Service Advantages Sample Specifications Library Sequencing Strategy Recommended data output Quality control Bisulfite ## Reduced Representation Bisulfite Sequencing (RRBS) [Reduced Representation Bisulfite Sequencing (RRBS)](https://www.bmkgene.com/reduced-representation-bisulfite-equencing-product/): Reduced representation bisulfite sequencing (RRBS) relies on the enrichment of CpG island-rich regions by MspI cleavage followed by size selection of ## PacBio-Full-length Transcriptome (Non-Reference) [PacBio-Full-length Transcriptome (Non-Reference)](https://www.bmkgene.com/pacbio-full-length-transcriptome-non-reference-2-product/):Raw data procession CCS extraction Full-length non-chimeric(FLNC) reads identification Consensus transcripts identification Bioinformatics Data ## OEM/ODM Manufacturer Pacbio Sequencing - Evolutionary Genetics - Biomarker [OEM/ODM Manufacturer Pacbio Sequencing - Evolutionary Genetics - Biomarker](https://www.bmkgene.com/oemodm-manufacturer-pacbio-sequencing-evolutionary-genetics-biomarker-product/): Service Advantages Service Specifications Bioinformatics analyses ü Whole genome resequencing ü Data processing ü SNP/Indel calling ## Hot sale Factory Mrna Seq Provider - Comparative Genomics - Biomarker [Hot sale Factory Mrna Seq Provider - Comparative Genomics - Biomarker](https://www.bmkgene.com/hot-sale-factory-mrna-seq-provider-comparative-genomics-biomarker-product/): Service Advantages Service Specifications Bioinformatics analyses ü Whole genome resequencing ü Data processing ü SNP/Indel calling ## Discount Price Dna Sequencing Illumina - Whole genome bisulfite sequencing - Biomarker [Discount Price Dna Sequencing Illumina - Whole genome bisulfite sequencing - Biomarker](https://www.bmkgene.com/discount-price-dna-sequencing-illumina-whole-genome-bisul%ef%ac%81te-sequencing-biomarker-product/):Service Advantages Sample Requirements Service Specifications Platform: NovaSeq 6000 platform, PE150 Recommended Sequencing Depth :≥30× coverage ## 2021 Latest Design Nanopore Sequencing Cost - 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Small RNA Sequencing--BMKGENE--2023.12 [Small RNA Sequencing--BMKGENE--2023.12](https://www.bmkgene.com/brochure/small-rna-sequencing-bmkgene-2023-05/):Small RNA Sequencing--BMKGENE--2023.12 ## Spatial Transcriptome Sequencing--BMKGENE--2023.05 [Spatial Transcriptome Sequencing--BMKGENE--2023.05](https://www.bmkgene.com/brochure/spatial-transcriptome-sequencing-bmkgene-2023-05/):Spatial Transcriptome Sequencing--BMKGENE--2023.05 ## BMKMANU S1000 Spatial Transcriptome Sequencing--BMKGENE--2023.05 [BMKMANU S1000 Spatial Transcriptome Sequencing--BMKGENE--2023.05](https://www.bmkgene.com/brochure/bmkmanu-s1000-spatial-transcriptome-sequencing-bmkgene-2023-05/):BMKMANU S1000 Spatial Transcriptome Sequencing--BMKGENE--2023.05 ## Full-length Transcriptome Sequencing-Nanopore--BMKGENE--2023.12 [Full-length Transcriptome Sequencing-Nanopore--BMKGENE--2023.12](https://www.bmkgene.com/brochure/full-length-transcriptome-sequencing-nanopore-bmkgene-2023-05/):Full-length Transcriptome Sequencing-Nanopore--BMKGENE--2023.12 ## Full-length Transcriptome Sequencing-PacBio--BMKGENE--2023.12 [Full-length Transcriptome Sequencing-PacBio--BMKGENE--2023.12](https://www.bmkgene.com/brochure/full-length-transcriptome-sequencing-pacbio-bmkgene-2023-05/):Full-length Transcriptome Sequencing-PacBio--BMKGENE--2023.12 ## Single-nucleus RNA Sequencing--BMKGENE--2023.05 [Single-nucleus RNA Sequencing--BMKGENE--2023.05](https://www.bmkgene.com/brochure/single-nucleus-rna-sequencing-bmkgene-2023-05/):Single-nucleus RNA Sequencing--BMKGENE--2023.05 ## 16S18SITS Amplicon Sequencing--BMKGENE--2023.12 [16S18SITS Amplicon Sequencing--BMKGENE--2023.12](https://www.bmkgene.com/brochure/16s18sits-amplicon-sequencing-bmkgene-2023-05/):16S18SITS Amplicon Sequencing--BMKGENE--2023.12 ## Metagenomics Sequencing--BMKGENE-2023.12 [Metagenomics Sequencing--BMKGENE-2023.12](https://www.bmkgene.com/brochure/copy-shot-gun-metagenomics-sequencing-bmkgene-2023-02/):Metagenomics Sequencing--BMKGENE-2023.12 ## Shot-gun Metagenomics Sequencing--BMKGENE--2023.02 [Shot-gun Metagenomics Sequencing--BMKGENE--2023.02](https://www.bmkgene.com/brochure/shot-gun-metagenomics-sequencing-bmkgene-2023-02/):Shot-gun Metagenomics Sequencing--BMKGENE--2023.02 ## Specific-Locus Amplified Fragment Sequencing (SLAF-Seq)--BMKGENE--2023.02 [Specific-Locus Amplified Fragment Sequencing (SLAF-Seq)--BMKGENE--2023.02](https://www.bmkgene.com/brochure/specific-locus-amplified-fragment-sequencing-slaf-seq-bmkgene-2023-02/):Specific-Locus Amplified Fragment Sequencing (SLAF-Seq)--BMKGENE--2023.02 ## De novo Full-length mRNA(PacBio)--BMKGENE--2023.02 [De novo Full-length mRNA(PacBio)--BMKGENE--2023.02](https://www.bmkgene.com/brochure/de-novo-full-length-mrnapacbio-bmkgene-2023-02/):De novo Full-length mRNA(PacBio)--BMKGENE--2023.02 ## De Novo Genome Assemble-Flyer [De Novo Genome Assemble-Flyer](https://www.bmkgene.com/brochure/de-novo-genome-assemble-flyer/):De Novo Genome Assemble-Flyer ## Plant and Animal Whole Genome Re-sequencing--BMKGENE--2023.02 [Plant and Animal Whole Genome Re-sequencing--BMKGENE--2023.02](https://www.bmkgene.com/brochure/plant-and-animal-whole-genome-re-sequencing-bmkgene-2023-02/):Plant and Animal Whole Genome Re-sequencing--BMKGENE--2023.02 ## Human Whole Genome Sequencing and Whole Exome Sequencing--BMKGENE-2023.02 [Human Whole Genome Sequencing and Whole Exome Sequencing--BMKGENE-2023.02](https://www.bmkgene.com/brochure/human-whole-genome-sequencing-and-whole-exome-sequencing-bmkgene-2023-02/):Human Whole Genome Sequencing and Whole Exome Sequencing--BMKGENE-2023.02 ## featured_publication link [featured_publication](https://www.bmkgene.com/featured_publication/) ## Featured Publication -- A haplotype-resolved chromosomal reference genome for the porcini mushroom Boletus edulis [Featured Publication -- A haplotype-resolved chromosomal reference genome for the porcini mushroom Boletus edulis](https://www.bmkgene.com/featured_publication/featured-publication-a-haplotype-resolved-chromosomal-reference-genome-for-the-porcini-mushroom-boletus-edulis/):G3 just served the porcini mushroom of genomes!  We're thrilled to announce the first haplotype-resolved chromosomal reference genome for the pr ## Featured Publication -- Genomic and epigenomic insight into giga-chromosome architecture and adptive evolution of royal lily (Lilium regale) [Featured Publication -- Genomic and epigenomic insight into giga-chromosome architecture and adptive evolution of royal lily (Lilium regale)](https://www.bmkgene.com/featured_publication/featured-publication-genomic-and-epigenomic-insight-into-giga-chromosome-architecture-and-adptive-evolution-of-royal-lily-lilium-regale/):BREAKTHROUGH ALERT! We're thrilled to announce the publication of the highest-quality chromosome-level genome assembly (35.6 Gb) for Lilium regale ## Featured Publication -- Transcriptome Analysis Reveals the Requirement of the TGF-β Pathway in Ascidian Tail Regression [Featured Publication -- Transcriptome Analysis Reveals the Requirement of the TGF-β Pathway in Ascidian Tail Regression](https://www.bmkgene.com/featured_publication/featured-publication-transcriptome-analysis-reveals-the-requirement-of-the-tgf-%ce%b2-pathway-in-ascidian-tail-regression/):New Breakthrough in Developmental Biology!  Researchers just cracked the code on extreme-speed metamorphosis in the sea squirt Styela clava! Publi ## Featured Publication - Spatiotemporal Transcriptomic Atlas Reveals the Regulatory Mechanisms Underlying Early Inflorescence Development and Sex Differentiation in Spinach [Featured Publication - Spatiotemporal Transcriptomic Atlas Reveals the Regulatory Mechanisms Underlying Early Inflorescence Development and Sex Differentiation in Spinach](https://www.bmkgene.com/featured_publication/featured-publication-spatiotemporal-transcriptomic-atlas-reveals-the-regulatory-mechanisms-underlying-early-inflorescence-development-and-sex-differentiation-in-spinach/):New Milestone in Spinach Research! On June 26, 2025, a groundbreaking study in Advanced Science unveiled the spatiotemporal transcriptomic atlas of ## Featured Publication - TRAPping the effects of tobacco smoking: the regulation and function of Acp5 expression in lung macrophages [Featured Publication - TRAPping the effects of tobacco smoking: the regulation and function of Acp5 expression in lung macrophages](https://www.bmkgene.com/featured_publication/featured-publication-trapping-the-effects-of-tobacco-smoking-the-regulation-and-function-of-acp5-expression-in-lung-macrophages/):Unmasking Tobacco's Attack on Lung Defenders! A breakthrough study in the American Journal of Physiology - Lung Cellular and Molecular Physiology r ## Featured Publication - Independent evolutionary deterioration of the oxygen-transport system in Asian noodlefishes and Antarctic icefishes [Featured Publication - Independent evolutionary deterioration of the oxygen-transport system in Asian noodlefishes and Antarctic icefishes](https://www.bmkgene.com/featured_publication/featured-publication-independent-evolutionary-deterioration-of-the-oxygen-transport-system-in-asian-noodlefishes-and-antarctic-icefishes/):Unlocking Evolutionary Secrets!  Understanding evolutionary mechanisms is key to decoding species and phenotypic diversity. Fishes, with their divers ## Featured Publication - Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo [Featured Publication - Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo](https://www.bmkgene.com/featured_publication/featured-publication-interplay-between-chemotaxis-quorum-sensing-and-metabolism-regulates-escherichia-coli-salmonella-typhimurium-interactions-in-vivo/):Exploring Bacterial Interactions: Chemotaxis, Quorum Sensing, and Metabolism in the Gut Ever wondered how bacteria navigate and compete in the complex ## Featured Publication - Spatial and Single-Cell Transcriptomics Reveal Cellular Heterogeneity and a Novel Cancer-Promoting Treg Cell Subset in Human Clear-Cell Renal Cell Carcinoma [Featured Publication - Spatial and Single-Cell Transcriptomics Reveal Cellular Heterogeneity and a Novel Cancer-Promoting Treg Cell Subset in Human Clear-Cell Renal Cell Carcinoma](https://www.bmkgene.com/featured_publication/featured-publication-spatial-and-single-cell-transcriptomics-reveal-cellular-heterogeneity-and-a-novel-cancer-promoting-treg-cell-subset-in-human-clear-cell-renal-cell-carcinoma/):Unlock Cancer's Hidden Complexity with BMKMANU S-Series Spatial Transcriptomics!  A groundbreaking study in the Journal for ImmunoTherapy of Cancer ## Featured Publication - Fully Phased Population-Prevalent East African Cattle BoLA-I Alleles Determined Using PacBio HiFi Long-Read Sequencing Represent Five Novel Specifications With Distinctive Peptide Binding Potential [Featured Publication - Fully Phased Population-Prevalent East African Cattle BoLA-I Alleles Determined Using PacBio HiFi Long-Read Sequencing Represent Five Novel Specifications With Distinctive Peptide Binding Potential](https://www.bmkgene.com/featured_publication/featured-publication-fully-phased-population-prevalent-east-african-cattle-bola-i-alleles-determined-using-pacbio-hifi-long-read-sequencing-represent-five-novel-specifications-with-distinctive-pepti/):Unlocking Genetic Resilience in East African Cattle!  A groundbreaking study in HLA reveals how East African cattle combat local diseases through u ## Featured Publication - CCR2+ monocytes drive memory CD8+ T-cell differentiation via membrane-bound TGF-β [Featured Publication - CCR2+ monocytes drive memory CD8+ T-cell differentiation via membrane-bound TGF-β](https://www.bmkgene.com/featured_publication/featured-publication-ccr2-monocytes-drive-memory-cd8-t-cell-differentiation-via-membrane-bound-tgf-%ce%b2/):Breaking News in Spatial Immunology!On June 3, 2025, a landmark study led by collaborative teams was published in Cellular & Molecular Immunology ## Featured Publication -- Monosaccharides drive Salmonella gut colonization in a context-dependent or -independent manner [Featured Publication -- Monosaccharides drive Salmonella gut colonization in a context-dependent or -independent manner](https://www.bmkgene.com/featured_publication/featured-publication-monosaccharides-drive-salmonella-gut-colonization-in-a-context-dependent-or-independent-manner/):New Research Alert! Discover how Salmonella outsmarts our gut defenses! A groundbreaking study published in Nature Communications unveils how monosacc ## Featured Publication -- A comprehensive omics resource and genetic tools for functional genomics research and genetic improvement of sorghum [Featured Publication -- A comprehensive omics resource and genetic tools for functional genomics research and genetic improvement of sorghum](https://www.bmkgene.com/featured_publication/featured-publication-a-comprehensive-omics-resource-and-genetic-tools-for-functional-genomics-research-and-genetic-improvement-of-sorghum/):Groundbreaking Research Alert! We're thrilled to spotlight a landmark paper published in Molecular Plant (March 7, 2025): "A comprehensive omics re ## Featured Publication -- Diversity and Plant Growth-Promoting Properties of Rhodiola rosea Root Endophytic Bacteria [Featured Publication -- Diversity and Plant Growth-Promoting Properties of Rhodiola rosea Root Endophytic Bacteria](https://www.bmkgene.com/featured_publication/featured-publication-diversity-and-plant-growth-promoting-properties-of-rhodiola-rosea-root-endophytic-bacteria/):Unlocking the Secret Life of Plants: Meet Rhodiola's Tiny Superheroes!A groundbreaking study in Microorganisms reveals the hidden world of Rhodiola ## Featured Publication -- Single-Cell and Spatial Transcriptomics Reveals a Stereoscopic Response of Rice Leaf Cells to Magnaporthe oryzae Infection [Featured Publication -- Single-Cell and Spatial Transcriptomics Reveals a Stereoscopic Response of Rice Leaf Cells to Magnaporthe oryzae Infection](https://www.bmkgene.com/featured_publication/featured-publication-single-cell-and-spatial-transcriptomics-reveals-a-stereoscopic-response-of-rice-leaf-cells-to-magnaporthe-oryzae-infection/):Exciting Breakthrough in Rice Research! On March 24, 2025, a groundbreaking study titled “Single-Cell and Spatial Transcriptomics Reveals a Ster ## Featured Publication -- High-quality faba bean reference transcripts generated using PacBio and Illumina RNA-seq data [Featured Publication -- High-quality faba bean reference transcripts generated using PacBio and Illumina RNA-seq data](https://www.bmkgene.com/featured_publication/featured-publication-high-quality-faba-bean-reference-transcripts-generated-using-pacbio-and-illumina-rna-seq-data/):Unlocking the Secrets of Faba Beans: A High-Quality Transcriptome Breakthrough! Published in Scientific Data, "High-quality faba bean reference transc ## Featured Publication -- Phylogenomic Analysis and SNP Fingerprinting Construction of Camellia oleifera Abel. Germplasm Resources Using SLAF-seq Technology [Featured Publication -- Phylogenomic Analysis and SNP Fingerprinting Construction of Camellia oleifera Abel. Germplasm Resources Using SLAF-seq Technology](https://www.bmkgene.com/featured_publication/featured-publication-phylogenomic-analysis-and-snp-fingerprinting-construction-of-camellia-oleifera-abel-germplasm-resources-using-slaf-seq-technology/):Exciting Breakthrough in Camellia oleifera Genomics!On April 2, 2025, Industrial Crops & Products published groundbreaking research titled “P ## Featured Publication -- Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression [Featured Publication -- Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression](https://www.bmkgene.com/featured_publication/featured-publication-splicing-factor-pqbp1-curtails-bax-expression-to-promote-ovarian-cancer-progression/):New Breakthrough in Ovarian Cancer Research!  A groundbreaking study published in Advanced Science titled "Splicing Factor PQBP1 Curtails BAX Expr ## Featured Publication -- Super Pangenome of Vitis Identifies Downy Mildew Resistance Genes for Grapevine Improvement [Featured Publication -- Super Pangenome of Vitis Identifies Downy Mildew Resistance Genes for Grapevine Improvement](https://www.bmkgene.com/featured_publication/featured-publication-super-pangenome-of-vitis-identifies-downy-mildew-resistance-genes-for-grapevine-improvement/):Grape Genome Research Reaches New Heights! BMKGENE Proudly Contributes to Groundbreaking Study! In a landmark achievement for grape genomics, BMKGEN ## Featured Publication -- Adventitious embryonic causal gene FhRWp regulates multiple developmental phenotypes in citrus reproduction [Featured Publication -- Adventitious embryonic causal gene FhRWp regulates multiple developmental phenotypes in citrus reproduction](https://www.bmkgene.com/featured_publication/featured-publication-adventitious-embryonic-causal-gene-fhrwp-regulates-multiple-developmental-phenotypes-in-citrus-reproduction/):Citrus plants are super interesting for scientists studying asexual reproduction, thanks to a gene called RWP. This gene controls the formation of ext ## Featured Publication - T2T Genome, Pan-Genome Analysis and Heat Stress Response Genes in Rhododendron Species [Featured Publication - T2T Genome, Pan-Genome Analysis and Heat Stress Response Genes in Rhododendron Species](https://www.bmkgene.com/featured_publication/featured-publication-t2t-genome-pan-genome-analysis-and-heat-stress-response-genes-in-rhododendron-species/):On March 5th, researchers from BMKGENE and collaborators achieved a scientific milestone with the publication of their groundbreaking study "T2T ## Featured Publication - The regulatary effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the machanism behind Candida albicans abundance and macrophage polarization [Featured Publication - The regulatary effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the machanism behind Candida albicans abundance and macrophage polarization](https://www.bmkgene.com/featured_publication/featured-publication-the-regulatary-effect-of-chitooligosaccharides-on-islet-inflammation-in-t2d-individuals-after-islet-cell-transplantation-the-machanism-behind-candida-albicans-abundance-and-mac/):  Groundbreaking Discovery in Type 2 Diabetes (T2D) Research! A landmark study published in the prestigious journal Gut Microbes has unveiled h ## Featured Publication——Haplotype-resolved genome of a papeda provides insights into the geographical origin and evolution of Citrus [Featured Publication——Haplotype-resolved genome of a papeda provides insights into the geographical origin and evolution of Citrus](https://www.bmkgene.com/featured_publication/featured-publication-haplotype-resolved-genome-of-a-papeda-provides-insights-into-the-geographical-origin-and-evolution-of-citrus/):Exciting news! A landmark study supported by BMKGENE was recently published in the Journal of Integrative Plant Biology titled "Haplotype-resolved gen ## Featured Publication——Sour Neuronal Signalling Attenuates Macrophage-Mediated Liver Injury [Featured Publication——Sour Neuronal Signalling Attenuates Macrophage-Mediated Liver Injury](https://www.bmkgene.com/featured_publication/featured-publication-sour-neuronal-signalling-attenuates-macrophage-mediated-liver-injury/):Exciting News! In March 2025, a groundbreaking study by BMKGENE's clients was published in the Journal of Hepatology, titled "Sour Neuronal Signalli ## Featured Publication - Dysbiosis of infant gut microbiota is related to the altered fatty acid composition of human milk from mothers with gestational diabetes mellitus: a prospective cohort study [Featured Publication - Dysbiosis of infant gut microbiota is related to the altered fatty acid composition of human milk from mothers with gestational diabetes mellitus: a prospective cohort study](https://www.bmkgene.com/featured_publication/featured-publication-dysbiosis-of-infant-gut-microbiota-is-related-to-the-altered-fatty-acid-composition-of-human-milk-from-mothers-with-gestational-diabetes-mellitus-a-prospective-cohort-study/):The article published in Gut Microbes, Dysbiosis of infant gut microbiota is related to the altered fatty acid composition of human milk from mothers ## Featured Publication - CcNFYB3 - CcMATE35 and LncRNA CcLTCS - CcCS modules jointly regulate the efflux and synthesis of citrate to enhance aluminium tolerance in pigeon pea [Featured Publication - CcNFYB3 - CcMATE35 and LncRNA CcLTCS - CcCS modules jointly regulate the efflux and synthesis of citrate to enhance aluminium tolerance in pigeon pea](https://www.bmkgene.com/featured_publication/featured-publication-ccnfyb3-ccmate35-and-lncrna-ccltcs-cccs-modules-jointly-regulate-the-efflux-and-synthesis-of-citrate-to-enhance-aluminium-tolerance-in-pigeon-pea/):The article, titled "CcNFYB3 - CcMATE35 and LncRNA CcLTCS - CcCS modules jointly regulate the efflux and synthesis of citrate to enhance aluminium tol ## Featured Publication - The Telomere-to-Telomere (T2T) Level Genome of Sweet Oranges [Featured Publication - The Telomere-to-Telomere (T2T) Level Genome of Sweet Oranges](https://www.bmkgene.com/featured_publication/featured-publication-the-telomere-to-telomere-t2t-level-genome-of-sweet-oranges/):Achievement Unlocked: The Telomere-to-Telomere (T2T) Level Genome of Sweet Oranges! A more contiguous reference genome is of great significance for g ## Featured Publication - The interaction and response of gut microbes to exposure to chiral ethiprole in honeybees (Apis mellifera) [Featured Publication - The interaction and response of gut microbes to exposure to chiral ethiprole in honeybees (Apis mellifera)](https://www.bmkgene.com/featured_publication/featured-publication-the-interaction-and-response-of-gut-microbes-to-exposure-to-chiral-ethiprole-in-honeybees-apis-mellifera/): Discover cutting-edge insights in “Journal of Hazardous Materials”! The interaction and response of gut microbes to exposure to chiral ethiprole ## Featured Publication - Spatiotemporal dynamics of early oogenesis in pigs [Featured Publication - Spatiotemporal dynamics of early oogenesis in pigs](https://www.bmkgene.com/featured_publication/featured-publication-spatiotemporal-dynamics-of-early-oogenesis-in-pigs/):Congratulations! In January 2025, One client of BMKGENE published a research paper titled "Spatiotemporal dynamics of early oogenesis in pigs" in the ## Featured Publications - Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillus–bile acid–intestinal farnesoid X receptor axis based on multiomics integration analysis [Featured Publications - Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillus–bile acid–intestinal farnesoid X receptor axis based on multiomics integration analysis](https://www.bmkgene.com/featured_publication/featured-publications-mineral-crude-drug-mirabilite-mangxiao-inhibits-the-occurrence-of-colorectal-cancer-by-regulating-the-lactobacillus-bile-acid-intestinal-farnesoid-x-receptor/):The article published in MedComm, Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillu ## Featured Publication - BACH2-mediated CD28 and CD40LG axes contribute to pathogenesis and progression of T-cell lymphoblastic leukemia [Featured Publication - BACH2-mediated CD28 and CD40LG axes contribute to pathogenesis and progression of T-cell lymphoblastic leukemia](https://www.bmkgene.com/featured_publication/featured-publication-bach2-mediated-cd28-and-cd40lg-axes-contribute-to-pathogenesis-and-progression-of-t-cell-lymphoblastic-leukemia/): A groundbreaking study published in Cell Death & Disease, BACH2-mediated CD28 and CD40LG axes contribute to pathogenesis and progression of T-cel ## Featured Publication - SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia [Featured Publication - SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia](https://www.bmkgene.com/featured_publication/featured-publication-sars-cov-2-n-protein-induced-dicer-xpo5-srsf3-and-hnrnpa3-downregulation-causes-pneumonia/): The article published Nature Communications, SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia. This study ## Featured Publication - Spatial Transcriptome Analysis Reveals De Novo Regeneration of Poplar Roots [Featured Publication - Spatial Transcriptome Analysis Reveals De Novo Regeneration of Poplar Roots](https://www.bmkgene.com/featured_publication/featured-publication-spatial-transcriptome-analysis-reveals-de-novo-regeneration-of-poplar-roots/):We are thrilled to announce a significant achievement by our partner - the publication of a research paper titled 'Spatial Transcriptome Analysis Reve ## Featured Publication - Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut. Resource competition is a driver of gut microbiota composition [Featured Publication - Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut. Resource competition is a driver of gut microbiota composition](https://www.bmkgene.com/featured_publication/featured-publication-non-canonical-start-codons-confer-context-dependent-advantages-in-carbohydrate-utilization-for-commensal-e-coli-in-the-murine-gut-resource-competition-is-a-driver-of-gut-micro/):The article published in Nature Microbiology, Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal ## Featured Publication - The complete genome assembly of Nicotiana benthamiana reveals the genetic and epigenetic landscape of centromeres [Featured Publication - The complete genome assembly of Nicotiana benthamiana reveals the genetic and epigenetic landscape of centromeres](https://www.bmkgene.com/featured_publication/featured-publication-the-complete-genome-assembly-of-nicotiana-benthamiana-reveals-the-genetic-and-epigenetic-landscape-of-centromeres/):Recently, the research findings of Dr. Guo Li's team on the complete genome assembly of Nicotiana benthamiana, titled "The complete genome assembly of ## Featured Publication - Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation [Featured Publication - Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation](https://www.bmkgene.com/featured_publication/featured-publication-klotho-derived-peptide-1-inhibits-cellular-senescence-in-the-fibrotic-kidney-by-restoring-klotho-expression-via-posttranscriptional-regulation/):The article published in Theranostics, Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via ## Featured Publication - MolluscDB2.0: a comprehensive functional and evolutionary genomics database for over 1400 molluscan species [Featured Publication - MolluscDB2.0: a comprehensive functional and evolutionary genomics database for over 1400 molluscan species](https://www.bmkgene.com/featured_publication/featured-publication-molluscdb-2-0-a-comprehensive-functional-and-evolutionary-genomics-database-for-over-1400-molluscan-species/):Another Success Story in BMKGENE's Genomics Database Construction! Exciting news today as our client's groundbreaking work was published in the presti ## Featured Publication - Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection [Featured Publication - Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection](https://www.bmkgene.com/featured_publication/featured-publication-dicer-2-mutations-in-aedes-aegypti-cells-lead-to-a-diminished-antiviral-function-against-rift-valley-fever-virus-and-bunyamwera-virus-infection/):The article published in Journal Of General Virology, Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Va ## Featured Publication - Tracing the evolutionary and genetic footprints of atmospheric tillandsioids transition from land to air [Featured Publication - Tracing the evolutionary and genetic footprints of atmospheric tillandsioids transition from land to air](https://www.bmkgene.com/featured_publication/featured-publication-tracing-the-evolutionary-and-genetic-footprints-of-atmospheric-tillandsioids-transition-from-land-to-air/):Exciting news! Another breakthrough application of BMKMANU Spatial Transcriptomics Technology in the plant domain! Our client's pioneering study, publ ## Featured Publication - Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma Tissue [Featured Publication - Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma Tissue](https://www.bmkgene.com/featured_publication/featured-publication-integrative-identification-by-hi-c-revealed-distinct-advanced-structural-variations-in-lung-adenocarcinoma-tissue/):The article published in Phenomics, titled "Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma ## Featured Publication - Ecological adaptation shaped the genetic structure of homoploid ferns against strong dispersal capacity [Featured Publication - Ecological adaptation shaped the genetic structure of homoploid ferns against strong dispersal capacity](https://www.bmkgene.com/featured_publication/featured-publication-ecological-adaptation-shaped-the-genetic-structure-of-homoploid-ferns-against-strong-dispersal-capacity/):SLAF-seq has found notable applications! Today, let's delve into a practical example of SLAF's utilization in population evolutionary studies. In an a ## Featured Publication - ippo Pathway Activation in Aged Mesenchymal Stem Cells Contributes to the Dysregulation of Hepatic Inflammation in Aged Mice [Featured Publication - ippo Pathway Activation in Aged Mesenchymal Stem Cells Contributes to the Dysregulation of Hepatic Inflammation in Aged Mice](https://www.bmkgene.com/featured_publication/featured-publication-ippo-pathway-activation-in-aged-mesenchymal-stem-cells-contributes-to-the-dysregulation-of-hepatic-inflammation-in-aged-mice/):The article published in Advanced Science, Hippo Pathway Activation in Aged Mesenchymal Stem Cells Contributes to the Dysregulation of Hepatic Inflamm ## Featured Publication - Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single-cell resolution [Featured Publication - Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single-cell resolution](https://www.bmkgene.com/featured_publication/featured-publication-molecular-and-spatial-signatures-of-human-and-rat-corpus-cavernosum-physiopathological-processes-at-single-cell-resolution-2/):Exciting News! In September 2024, our clients successfully published the first human and rat corpus cavernosum spatial transcriptomics map in the acad ## Featured Publication - Metabolomic and metagenomic analyses of the Chinese mitten crab Eriocheir sinensis after challenge with Metschnikowia bicuspidata [Featured Publication - Metabolomic and metagenomic analyses of the Chinese mitten crab Eriocheir sinensis after challenge with Metschnikowia bicuspidata](https://www.bmkgene.com/featured_publication/featured-publication-metabolomic-and-metagenomic-analyses-of-the-chinese-mitten-crab-eriocheir-sinensis-after-challenge-with-metschnikowia-bicuspidata/):The article published in Frontiers in Microbiology, Metabolomic and metagenomic analyses of the Chinese mitten crab Eriocheir sinensis after challenge ## Featured Publication - Molecular and Spatial Signatures of Human and Rat Corpus Cavernosum Physiopathological Processes at Single-Cell Resolution [Featured Publication - Molecular and Spatial Signatures of Human and Rat Corpus Cavernosum Physiopathological Processes at Single-Cell Resolution](https://www.bmkgene.com/featured_publication/featured-publication-molecular-and-spatial-signatures-of-human-and-rat-corpus-cavernosum-physiopathological-processes-at-single-cell-resolution/):We are thrilled to announce that the research article titled "Molecular and Spatial Signatures of Human and Rat Corpus Cavernosum Physiopathological P ## Featured Publication - EXPLORING ROLES OF MIR-885-5P IN HEPATOCELLULAR CARCINOMA [Featured Publication - EXPLORING ROLES OF MIR-885-5P IN HEPATOCELLULAR CARCINOMA](https://www.bmkgene.com/featured_publication/featured-publication-exploring-roles-of-mir-885-5p-in-hepatocellular-carcinoma/):The article published in Procedia of Multidisciplinary Research, EXPLORING ROLES OF MIR-885-5P IN HEPATOCELLULAR CARCINOMA. In this study, MicroRNAs ( ## Featured Publication - Chromosome-scale genome, together with transcriptome and metabolome, provides insights into the evolution and anthocyanin biosynthesis of Rubus rosaefolius Sm. (Rosaceae) [Featured Publication - Chromosome-scale genome, together with transcriptome and metabolome, provides insights into the evolution and anthocyanin biosynthesis of Rubus rosaefolius Sm. (Rosaceae)](https://www.bmkgene.com/featured_publication/featured-publication-chromosome-scale-genome-together-with-transcriptome-and-metabolome-provides-insights-into-the-evolution-and-anthocyanin-biosynthesis-of-rubus-rosaefolius-sm-rosaceae/):The rapid advancement of sequencing technology has led to the emergence of various omics fields, from DNA and RNA to trending metabolomics, each offer ## Featured Publication - Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells [Featured Publication - Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells](https://www.bmkgene.com/featured_publication/featured-publication-acetyl-coa-metabolism-maintains-histone-acetylation-for-syncytialization-of-human-placental-trophoblast-stem-cells/):On July 30, 2024, One of our clients published a significant research finding in the international academic journal Cell Stem Cell. The research, titl ## Featured Publication - Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway [Featured Publication - Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway](https://www.bmkgene.com/featured_publication/featured-publication-aspergillus-fumigatus-hijacks-human-p11-to-redirect-fungal-containing-phagosomes-to-non-degradative-pathway-2/):The decision whether endosomes enter the degradative or recycling pathway in mammalian cells is of fundamental importance for pathogen killing, and it ## Featured Publication - Integration of ATAC-seq and RNA-seq Reveals the Dynamics of Chromatin Accessibility and Gene Expression in Zoysiagrass Response to Drought [Featured Publication - Integration of ATAC-seq and RNA-seq Reveals the Dynamics of Chromatin Accessibility and Gene Expression in Zoysiagrass Response to Drought](https://www.bmkgene.com/featured_publication/featured-publication-integration-of-atac-seq-and-rna-seq-reveals-the-dynamics-of-chromatin-accessibility-and-gene-expression-in-zoysiagrass-response-to-drought/):Multi-omics application article: Integration of ATAC-seq and RNA-seq Reveals the Dynamics of Chromatin Accessibility and Gene Expression in Zoysiagras ## Featured Publication - Comparative Transcriptome, and metabolome analysis reveals key regulatory defense networks and genes involved in enhanced salt tolerance of Actinidia (kiwifruit) [Featured Publication - Comparative Transcriptome, and metabolome analysis reveals key regulatory defense networks and genes involved in enhanced salt tolerance of Actinidia (kiwifruit)](https://www.bmkgene.com/featured_publication/featured-publication-comparative-transcriptome-and-metabolome-analysis-reveals-key-regulatory-defense-networks-and-genes-involved-in-enhanced-salt-tolerance-of-actinidia-kiwifruit/):The article, titled "Comparative Transcriptome, and metabolome analysis reveals key regulatory defense networks and genes involved in enhanced salt to ## Featured Publication – Postharvest quality and metabolism changes of daylily flower buds treated with hydrogen sulfide during storage [ Featured Publication – Postharvest quality and metabolism changes of daylily flower buds treated with hydrogen sulfide during storage](https://www.bmkgene.com/featured_publication/featured-publication-postharvest-quality-and-metabolism-changes-of-daylily-flower-buds-treated-with-hydrogen-sulfide-during-storage/):The article, titled"Postharvest quality and metabolism changes of daylily flower buds treated with hydrogen sulfide during storage", published in the ## Featured Publication - The comprehensive detection of miRNA, lncRNA, and circRNA in regulation of mouse melanocyte and skin development [Featured Publication - The comprehensive detection of miRNA, lncRNA, and circRNA in regulation of mouse melanocyte and skin development](https://www.bmkgene.com/featured_publication/featured-publication-the-comprehensive-detection-of-mirna-lncrna-and-circrna-in-regulation-of-mouse-melanocyte-and-skin-development/):The article, titled “the comprehensive detection of miRNA, lncRNA, and circRNA in regulation of mouse melanocyte and skin development”, was p ## Featured Publication - Telomere-to-telomere Citrullus Super-pangenome Provides Direction for Watermelon Breeding [Featured Publication - Telomere-to-telomere Citrullus Super-pangenome Provides Direction for Watermelon Breeding](https://www.bmkgene.com/featured_publication/featured-publication-telomere-to-telomere-citrullus-super-pangenome-provides-direction-for-watermelon-breeding/): A new successful case of BMKGENE! On July 8, 2024, a groundbreaking achievement was made in the field of watermelon research with the release of the ## Featured Publication - Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma [Featured Publication - Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma](https://www.bmkgene.com/featured_publication/featured-publication-epigenetic-and-transcriptional-activation-of-the-secretory-kinase-fam20c-as-an-oncogene-in-glioma-2/):The article, titled “Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma”, was published in Journal ## Featured Publication - Metabolomics and transcriptomic profiles reveal membrane lipid metabolism as a key factor in sliced taro browning [Featured Publication - Metabolomics and transcriptomic profiles reveal membrane lipid metabolism as a key factor in sliced taro browning](https://www.bmkgene.com/featured_publication/featured-publication-metabolomics-and-transcriptomic-profiles-reveal-membrane-lipid-metabolism-as-a-key-factor-in-sliced-taro-browning/): Congratulations to our clients on their recent achievements! On May 9, 2024, our clients successfully published a research paper in the international ## Featured Publication-MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato [Featured Publication-MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato](https://www.bmkgene.com/featured_publication/featured-publication-myc2-orchestrates-a-hierarchical-transcriptional-cascade-that-regulates-jasmonate-mediated-plant-immunity-in-tomato/):The article, “MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato”, was published ## Featured Publication-Phycoremediation and valorization of hypersaline pickled mustard wastewater via Chaetoceros muelleri and indigenous bacteria [Featured Publication-Phycoremediation and valorization of hypersaline pickled mustard wastewater via Chaetoceros muelleri and indigenous bacteria](https://www.bmkgene.com/featured_publication/featured-publication-phycoremediation-and-valorization-of-hypersaline-pickled-mustard-wastewater-via-chaetoceros-muelleri-and-indigenous-bacteria/):The article, titled “Phycoremediation and valorization of hypersaline pickled mustard wastewater via Chaetoceros muelleri and indigenous bacteria” ## Featured Publication-Chromosome-scale genome assembly clarifies the mechanism of flooding tolerance and evolutionary history of Myricaria laxiflora [Featured Publication-Chromosome-scale genome assembly clarifies the mechanism of flooding tolerance and evolutionary history of Myricaria laxiflora](https://www.bmkgene.com/featured_publication/featured-publication-chromosome-scale-genome-assembly-clarifies-the-mechanism-of-flooding-tolerance-and-evolutionary-history-of-myricaria-laxiflora/):Recently, the research finding from BMKGENE’s client was published in the journal “Industrial Crops & Products” under the title “Chromosom ## Featured Publication-SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors [Featured Publication-SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors](https://www.bmkgene.com/featured_publication/featured-publication-smad7-expression-in-car-t-cells-improves-persistence-and-safety-for-solid-tumors/):The article, titled “SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors”, was published in Cellular & Molecular ## Featured Publication-Enhancing pollutants removal in hospital wastewater: Comparative analysis of PAC coagulation vs. bio-contact oxidation, highlighting the impact of outdated treatment plants [Featured Publication-Enhancing pollutants removal in hospital wastewater: Comparative analysis of PAC coagulation vs. bio-contact oxidation, highlighting the impact of outdated treatment plants](https://www.bmkgene.com/featured_publication/featured-publication-enhancing-pollutants-removal-in-hospital-wastewater-comparative-analysis-of-pac-coagulation-vs-bio-contact-oxidation-highlighting-the-impact-of-outdated-treatment-plants/): The article, titled “Enhancing pollutants removal in hospital wastewater: Comparative analysis of PAC coagulation vs. bio-contact o ## Featured Publication-Unraveling the ecological mechanisms of Aluminum on microbial community succession in epiphytic biofilms on Vallisneria natans leaves: Novel insights from microbial interactions [Featured Publication-Unraveling the ecological mechanisms of Aluminum on microbial community succession in epiphytic biofilms on Vallisneria natans leaves: Novel insights from microbial interactions](https://www.bmkgene.com/featured_publication/featured-publication-unraveling-the-ecological-mechanisms-of-aluminum-on-microbial-community-succession-in-epiphytic-biofilms-on-vallisneria-natans-leaves-novel-insights-from-microbial-interactions/):The article, named "Unraveling the ecological mechanisms of Aluminum on microbial community succession in epiphytic biofilms on Vallisneria natans lea ## Featured Publication-Relationship between vaginal and oral microbiome in patients of human papillomavirus (HPV) infection and cervical cancer [Featured Publication-Relationship between vaginal and oral microbiome in patients of human papillomavirus (HPV) infection and cervical cancer](https://www.bmkgene.com/featured_publication/featured-publication-relationship-between-vaginal-and-oral-microbiome-in-patients-of-human-papillomavirus-hpv-infection-and-cervical-cancer/):The article, titled "Relationship between vaginal and oral microbiome in patients of human papillomavirus (HPV) infection and cervical cancer", was pu ## Featured Publication-Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of situ and invasive acral melanoma [Featured Publication-Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of situ and invasive acral melanoma](https://www.bmkgene.com/featured_publication/7552/):Exciting news! BMKGENE developed BMKMANU S series spatial transcriptomics chip with cell segmentation technology aided by the high-precision analysis ## Featured Publication-Characteristics of bacterial community and extracellular enzymes in response to atrazine application in black soil [Featured Publication-Characteristics of bacterial community and extracellular enzymes in response to atrazine application in black soil](https://www.bmkgene.com/featured_publication/featured-publication-characteristics-of-bacterial-community-and-extracellular-enzymes-in-response-to-atrazine-application-in-black-soil/):The article, titled "Characteristics of bacterial community and extracellular enzymes in response to atrazine application in black soil", was publish ## Featured Publication-Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature [Featured Publication-Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature](https://www.bmkgene.com/featured_publication/featured-publication-maternal-rna-transcription-in-dlk1-dio3-domain-is-critical-for-proper-development-of-the-mouse-placental-vasculature/):Unraveling Maternal RNA's Role in Placental Vasculature Development In a groundbreaking study published in Communications Biology, researchers delve i ## Featured Publication-Molecular basis of methyI-salicylate-mediated plant airborne defence [Featured Publication-Molecular basis of methyI-salicylate-mediated plant airborne defence](https://www.bmkgene.com/featured_publication/featured-publication-molecular-basis-of-methyi-salicylate-mediated-plant-airborne-defence/):Unveiling Plant Airborne Defense Mechanism!  Exciting findings from the latest Nature article, "Molecular Basis of Methyl-Salicylate Mediated Plant ## Featured Publication-A chromosome-level genome assembly of yellow stem borer (Scirpophaga incertulas) [Featured Publication-A chromosome-level genome assembly of yellow stem borer (Scirpophaga incertulas)](https://www.bmkgene.com/featured_publication/7542/):Exciting news in the world of genomics! "A chromosome-level genome assembly of yellow stem borer (Scirpophaga incertulas)" published in Scientific Dat ## Featured Publication-Combined transcriptomic and metabolomic analyses elucidate key salt-responsive biomarkers to regulate salt tolerance in cotton [Featured Publication-Combined transcriptomic and metabolomic analyses elucidate key salt-responsive biomarkers to regulate salt tolerance in cotton](https://www.bmkgene.com/featured_publication/featured-publication-combined-transcriptomic-and-metabolomic-analyses-elucidate-key-salt-responsive-biomarkers-to-regulate-salt-tolerance-in-cotton/):Exploring the molecular mechanism of salt tolerance in cotton! In one of BMKGENE's successful cases, recently published by Han et al. in "BMC Plant Bi ## Featured Publication-Gut bacteria alleviate smoking-related NASH by degrading gut nicotine [Featured Publication-Gut bacteria alleviate smoking-related NASH by degrading gut nicotine](https://www.bmkgene.com/featured_publication/7534/):New case: Gut microbiota & Non-Alcoholic Fatty Liver Disease An article, recently published in Nature, unveils a promising pathway in the fight ag ## Featured Publication-Chromosome-level genome assembly of Prunella vulgaris L. provides insights into pentacyclic triterpenoid biosynthesis [Featured Publication-Chromosome-level genome assembly of Prunella vulgaris L. provides insights into pentacyclic triterpenoid biosynthesis](https://www.bmkgene.com/featured_publication/featured-publication-chromosome-level-genome-assembly-of-prunella-vulgaris-l-provides-insights-into-pentacyclic-triterpenoid-biosynthesis/): BMKGENE Adds Another Successful Genome Assembly Case in 2024! Prunella vulgaris is one of the widely used traditional Chinese herbs. According to the ## Featured Publication-High-quality chromosome-level genome assembly and multi-omics analysis of rosemary (Salvia rosmarinus) reveals new insights into the environmental and genome adaptation [Featured Publication-High-quality chromosome-level genome assembly and multi-omics analysis of rosemary (Salvia rosmarinus) reveals new insights into the environmental and genome adaptation](https://www.bmkgene.com/featured_publication/featured-publication-high-quality-chromosome-level-genome-assembly-and-multi-omics-analysis-of-rosemary-salvia-rosmarinus-reveals-new-insights-into-the-environmental-and-genome-adaptation/): Breaking Ground in Plant Science! Recently, Zhang Dangquan and the research team at Henan Agricultural University achieved a remarkable feat – c ## Featured Publication-The Great Gobi A Strictly Protected Area: Characterization of Soil Bacterial Communities from Four Oases [Featured Publication-The Great Gobi A Strictly Protected Area: Characterization of Soil Bacterial Communities from Four Oases](https://www.bmkgene.com/featured_publication/featured-publication-the-great-gobi-a-strictly-protected-area-characterization-of-soil-bacterial-communities-from-four-oases/): BMKGENE's Contribution to Microbial Ecology Research in Extreme Environments  We are excited to share insights from a recent study published in  Mi ## Featured Publication-Comprehensive evaluation of circRNAs in cirrhotic cardiomyopathy before and after liver transplantation [Featured Publication-Comprehensive evaluation of circRNAs in cirrhotic cardiomyopathy before and after liver transplantation](https://www.bmkgene.com/featured_publication/featured-publication-comprehensive-evaluation-of-circrnas-in-cirrhotic-cardiomyopathy-before-and-after-liver-transplantation/): Exploring the Role of circRNAs in Cirrhotic Cardiomyopathy A recent article published in International Immunopharmacology delves into circRNAs and th ## Featured Publication—Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria [Featured Publication—Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria](https://www.bmkgene.com/featured_publication/featured-publication-ampicillin-controlled-glucose-metabolism-manipulates-the-transition-from-tolerance-to-resistance-in-bacteria/): Our bacterial whole genome sequencing and analysis services played a crucial role in a study published in Science Magazine. The research reveals tha ## Featured Publication—Synthetic bacterial consortia transplantation for the treatment of Gardnerella vaginalis-induced bacterial vaginosis in mice [Featured Publication—Synthetic bacterial consortia transplantation for the treatment of Gardnerella vaginalis-induced bacterial vaginosis in mice](https://www.bmkgene.com/featured_publication/featured-publication-synthetic-bacterial-consortia-transplantation-for-the-treatment-of-gardnerella-vaginalis-induced-bacterial-vaginosis-in-mice/): News in microbiome research! A recent publication in Microbiome(BMC journal) investigates Synthetic Bacterial Consortia Transplantation (SBCT) for G ## Featured Publication—Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development [Featured Publication—Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development](https://www.bmkgene.com/featured_publication/featured-publication-genetic-linkage-analysis-of-stable-qtls-in-gossypium-hirsutum-ril-population-revealed-function-of-ghcesa4-in-fiber-development/): Youlu Yuan and his team at the Chinese Academy of Agricultural Sciences (CAAS) Cotton Research Institute have successfully created a high-density gen ## Featured Publication—Gut microbiota-derived metabolites facilitate melatonin's neuroprotective properties in sleep deprivation-induced cognitive impairment [Featured Publication—Gut microbiota-derived metabolites facilitate melatonin's neuroprotective properties in sleep deprivation-induced cognitive impairment](https://www.bmkgene.com/featured_publication/featured-publication-gut-microbiota-derived-metabolites-facilitate-melatonins-neuroprotective-properties-in-sleep-deprivation-induced-cognitive-impairment/): BMKGENE provided microbial amplicon sequencing and non-target metabolome testing services for this study "Gut microbiota-derived metabolites facilita ## Featured Publication—Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease [Featured Publication—Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease](https://www.bmkgene.com/featured_publication/featured-publication-targeting-hnrnpc-suppresses-thyroid-follicular-epithelial-cell-apoptosis-and-necroptosis-through-m6a-modified-atf4-in-autoimmune-thyroid-disease/): The study published in Pharmacological Research titled "Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis thro ## Featured Publication—Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption [Featured Publication—Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption](https://www.bmkgene.com/featured_publication/featured-publication-3/): Acute Respiratory Distress Syndrome (ARDS) is an acute respiratory disease involving blood-gas barrier dysfunction. ARDS is primarily characterized b ## Featured Publication—Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum [Featured Publication—Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum](https://www.bmkgene.com/featured_publication/featured-publication-mapping-and-functional-dissection-of-the-rumpless-trait-in-piao-chicken-identifies-a-causal-loss-of-function-mutation-in-the-novel-gene-rum/): Another successful case of BMKGENE has been published online! On December 9, 2023, the article titled  "Mapping and functional dissection of the rum ## Featured Publication—Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring [Featured Publication—Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring](https://www.bmkgene.com/featured_publication/featured-publication-maternal-vitamin-b1-is-a-determinant-for-the-fate-of-primordial-follicle-formation-in-offspring/): BMKGENE provided sequencing and analysis services of 16S rDNA amplicon and metabolomics for the study  titled "Maternal vitamin B1 is a determinant ## Featured Publication—Allele-defined genome reveals biallelic differentiation during cassava evolution [Featured Publication—Allele-defined genome reveals biallelic differentiation during cassava evolution](https://www.bmkgene.com/featured_publication/featured-publication-allele-defined-genome-reveals-biallelic-differentiation-during-cassava-evolution/): BMKGENE has extensive experience in this area, here is a featured publication for Cassava published on Molecular Plant. Haplotype analysis can provi ## Featured Publication—Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs [Featured Publication—Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs](https://www.bmkgene.com/featured_publication/featured-publication-different-roles-of-host-and-habitat-in-determining-the-microbial-communities-of-plant-feeding-true-bugs/): BMKGENE provided full-length amplicon sequencing services for the study  titled “Different roles of host and habitat in determining the microbial ## Featured Publication—The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis [Featured Publication—The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis](https://www.bmkgene.com/featured_publication/featured-publication-the-nanoformula-of-zoledronic-acid-and-calcium-carbonate-targets-osteoclasts-and-reverses-osteoporosis/): BMKGENE provided long non-coding RNA sequencing services for the article "The nanoformula of zoledronic acid and calcium carbonate targets osteoclast ## Featured Publication—Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification [Featured Publication—Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification](https://www.bmkgene.com/featured_publication/featured-publication-comparative-analysis-of-pacbio-and-ont-rna-sequencing-methods-for-nemopilema-nomurai-venom-identification/):BMKGENE provided full-length transcriptome sequencing services using PacBio and ONT technologies for a study titled "Comparative analysis of PacBio an ## BMKGENE Experience of WGBS&RNA-seq Joint Analysis [BMKGENE Experience of WGBS&RNA-seq Joint Analysis](https://www.bmkgene.com/featured_publication/bmkgene-experience-of-wgbsrna-seq-joint-analysis/): DNA methylation is one of the most extensively studied epigenetic modifications. It plays a crucial role in genome stability, gene transcription regu ## Featured Publication—Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86 [Featured Publication—Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86](https://www.bmkgene.com/featured_publication/featured-publication-microbiome-metabolome-analysis-directed-isolation-of-rhizobacteria-capable-of-enhancing-salt-tolerance-of-sea-rice-86/): The article titled "Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86" published ## Featured Publication—Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs [Featured Publication—Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs](https://www.bmkgene.com/featured_publication/featured-publication-obese-ningxiang-pig-derived-microbiota-rewires-carnitine-metabolism-to-promote-muscle-fatty-acid-deposition-in-lean-dly-pigs/): BMKGENE provided full-length 16s amplicon sequencing and metagenomics sequencing services for the article “Obese Ningxiang pig-derived microbiota ## Featured Publication—Mining Genes Related to Fruit Quality in Sweet Oranges Based on Specific Locus Amplified Fragment Sequencing [Featured Publication—Mining Genes Related to Fruit Quality in Sweet Oranges Based on Specific Locus Amplified Fragment Sequencing](https://www.bmkgene.com/featured_publication/featured-publication-mining-genes-related-to-fruit-quality-in-sweet-oranges-based-on-specific-locus-amplified-fragment-sequencing/): One important horticultural characteristic that distinguishes navel oranges from other common sweet orange varieties is the presence of a navel on th ## Featured Publication—Capturing the microbial dark matter in desert soils using culturomics-based metagenomics and high-resolution analysis [Featured Publication—Capturing the microbial dark matter in desert soils using culturomics-based metagenomics and high-resolution analysis](https://www.bmkgene.com/featured_publication/featured-publication-capturing-the-microbial-dark-matter-in-desert-soils-using-culturomics-based-metagenomics-and-high-resolution-analysis/): BMKGENE provided full-length 16s amplicon sequencing and metagenomics sequencing services for this study  “Capturing the microbial dark matter in ## Featured Publication—The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius) [Featured Publication—The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius)](https://www.bmkgene.com/featured_publication/featured-publication-2/): BMKGENE provided 16s amplicon sequencing services for this study: The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalu ## Featured Publication—Genetic Diversity and Population Structure in Solanum nigrum Based on Single-Nucleotide Polymorphism (SNP) Markers [Featured Publication—Genetic Diversity and Population Structure in Solanum nigrum Based on Single-Nucleotide Polymorphism (SNP) Markers](https://www.bmkgene.com/featured_publication/featured-publication-genetic-diversity-and-population-structure-in-solanum-nigrum-based-on-single-nucleotide-polymorphism-snp-markers/): For large-scale populations, we recommend using specific-locus amplified fragment sequencing (SLAF) for genome sequencing and variant detection, enab ## Featured Publication—3D disorganization and rearrangement of genome provide insights into pathogenesis of non-alcoholic fatty liver disease (NAFLD) by integrated Hi-C, Nanopore, and RNA sequencing [Featured Publication—3D disorganization and rearrangement of genome provide insights into pathogenesis of non-alcoholic fatty liver disease (NAFLD) by integrated Hi-C, Nanopore, and RNA sequencing](https://www.bmkgene.com/featured_publication/featured-publication-3d-disorganization-and-rearrangement-of-genome-provide-insights-into-pathogenesis-of-non-alcoholic-fatty-liver-disease-nafld-by-integrated-hi-c-nanopore-and-rna-sequen/): BMKGENE provided Hi-C sequencing services for this study: 3D disorganization and rearrangement of genome provide insights into pathogenesis of non-al ## Featured Publication—Full-length transcriptome sequencing of lymphocytes respond to IFN-γ reveals a Th1-skewed immune response in flounder (Paralichthys olivaceus) [Featured Publication—Full-length transcriptome sequencing of lymphocytes respond to IFN-γ reveals a Th1-skewed immune response in flounder (Paralichthys olivaceus)](https://www.bmkgene.com/featured_publication/featured-publication-full-length-transcriptome-sequencing-of-lymphocytes-respond-to-ifn-%ce%b3-reveals-a-th1-skewed-immune-response-in-flounder-paralichthys-olivaceus/): BMKGENE provided full-length transcriptome sequencing services for this study : Full-length transcriptome sequencing of lymphocytes respond to IFN-γ ## Featured Publication—Saltwater intrusion affecting NO2− accumulation in demersal fishery species by bacterially mediated N-cycling [Featured Publication—Saltwater intrusion affecting NO2− accumulation in demersal fishery species by bacterially mediated N-cycling](https://www.bmkgene.com/featured_publication/featured-publication-saltwater-intrusion-affecting-no2%e2%88%92-accumulation-in-demersal-fishery-species-by-bacterially-mediated-n-cycling/): BMKGENE provided 16s amplicon and metagenomic sequencing services for this study： Saltwater intrusion affecting NO2− accumulation in demersal fis ## Featured Publication—STEEL enables high-resolution delineation of spatiotemporal transcriptomic data [Featured Publication—STEEL enables high-resolution delineation of spatiotemporal transcriptomic data](https://www.bmkgene.com/featured_publication/featured-publication-steel-enables-high-resolution-delineation-of-spatiotemporal-transcriptomic-data/): BMKGENE provided spatial transcriptome sequencing services for the study  "STEEL enables high-resolution delineation of spatiotemporal transcriptomi ## Featured Publication—Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma [Featured Publication—Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma](https://www.bmkgene.com/featured_publication/featured-publication-epigenetic-and-transcriptional-activation-of-the-secretory-kinase-fam20c-as-an-oncogene-in-glioma/):  BMKGENE provided ONT long-read nanopore RNA sequencing and ATAC-seq service for the study  "Epigenetic and transcriptional activation of the ## Featured Publication—A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via synergistic ROS augment and autophagy blockage [Featured Publication—A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via synergistic ROS augment and autophagy blockage](https://www.bmkgene.com/featured_publication/featured-publication-a-cascade-nanoreactor-for-enhancing-sonodynamic-therapy-on-colorectal-cancer-via-synergistic-ros-augment-and-autophagy-blockage/): BMKGENE provided transcriptome sequencing service for the study "A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via syn ## Featured Publication—Dynamic Changes in Butyrate Levels Regulate Satellite Cell Homeostasis by Preventing Spontaneous Activation During Aging [Featured Publication—Dynamic Changes in Butyrate Levels Regulate Satellite Cell Homeostasis by Preventing Spontaneous Activation During Aging](https://www.bmkgene.com/featured_publication/featured-publication-dynamic-changes-in-butyrate-levels-regulate-satellite-cell-homeostasis-by-preventing-spontaneous-activation-during-aging/): The article published in Science China-Life Sciences, "Dynamic Changes in Butyrate Levels Regulate Satellite Cell Homeostasis by Preventing Spontaneo ## Featured Publication—Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway [Featured Publication—Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway](https://www.bmkgene.com/featured_publication/featured-publication-aspergillus-fumigatus-hijacks-human-p11-to-redirect-fungal-containing-phagosomes-to-non-degradative-pathway/): BMKGENE provided RNA sequencing and analysis services for this study  "Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagoso ## Featured Publication—Wound infiltrating adipocytes are not myofibroblasts [Featured Publication—Wound infiltrating adipocytes are not myofibroblasts](https://www.bmkgene.com/featured_publication/featured-publication-wound-infiltrating-adipocytes-are-not-myofibroblasts/): BMKGENE provided bulk RNA sequencing and analysis services for this study: Wound infiltrating adipocytes are not myofibroblasts. The article was publ ## Featured Publication—Chromosome-level Wild Hevea brasiliensis Genome: Empowering Genomic-Assisted Breeding and Unearthing Vital Loci for Elevated Rubber Yield [Featured Publication—Chromosome-level Wild Hevea brasiliensis Genome: Empowering Genomic-Assisted Breeding and Unearthing Vital Loci for Elevated Rubber Yield](https://www.bmkgene.com/featured_publication/featured-publication-chromosome-level-wild-hevea-brasiliensis-genome-empowering-genomic-assisted-breeding-and-unearthing-vital-loci-for-elevated-rubber-yield/): Delve into the potential of studying wild variety of research species, exemplified by a pivotal case from BMKGENE's clients. Recently published in th ## Featured Publication—Photodynamic therapy improves the outcome of immune checkpoint inhibitors via remodelling anti-tumour immunity in patients with gastric cancer, which was published in Gastric Cancer [Featured Publication—Photodynamic therapy improves the outcome of immune checkpoint inhibitors via remodelling anti-tumour immunity in patients with gastric cancer, which was published in Gastric Cancer](https://www.bmkgene.com/featured_publication/featured-publication-photodynamic-therapy-improves-the-outcome-of-immune-checkpoint-inhibitors-via-remodelling-anti-tumour-immunity-in-patients-with-gastric-cancer-which-was-published-in-gast/): BMKGENE provided single-cell transcriptome sequencing and single-cell TCR sequencing and analysis services for this study : Photodynamic therapy impr ## Featured Publication—Haplotype-resolved genomes of wild octoploid progenitors illuminate genomic diversifications from wild relatives to cultivated strawberry [Featured Publication—Haplotype-resolved genomes of wild octoploid progenitors illuminate genomic diversifications from wild relatives to cultivated strawberry](https://www.bmkgene.com/featured_publication/featured-publication-haplotype-resolved-genomes-of-wild-octoploid-progenitors-illuminate-genomic-diversifications-from-wild-relatives-to-cultivated-strawberry/): We would like to offer our warmest congratulations to our esteemed clients for the successful publication of their outstanding research titled "Haplo ## Featured Publication—a potential Drosophila homologue of mammalian adhesion GPCRs, is involved in antitumor reactions to injected oncogenic cells in flies, which was published in PNAS, mthl1 [Featured Publication—a potential Drosophila homologue of mammalian adhesion GPCRs, is involved in antitumor reactions to injected oncogenic cells in flies, which was published in PNAS, mthl1](https://www.bmkgene.com/featured_publication/featured-publication-a-potential-drosophila-homologue-of-mammalian-adhesion-gpcrs-is-involved-in-antitumor-reactions-to-injected-oncogenic-cells-in-flies-which-was-published-in-pnas-mthl1/): BMKGENE provided spatial transcriptomics sequencing services for this study: a potential Drosophila homologue of mammalian adhesion GPCRs, is involve ## Featured Publication— Integrating Spatial Transcriptomics and Single-nucleus RNA Sequencing Reveals the Potential Therapeutic Strategies for Uterine Leiomyoma [Featured Publication— Integrating Spatial Transcriptomics and Single-nucleus RNA Sequencing Reveals the Potential Therapeutic Strategies for Uterine Leiomyoma](https://www.bmkgene.com/featured_publication/featured-publication-integrating-spatial-transcriptomics-and-single-nucleus-rna-sequencing-reveals-the-potential-therapeutic-strategies-for-uterine-leiomyoma/): BMKGENE provided spatial transcriptomics and single-nucleus RNA sequencing services for this study: Integrating Spatial Transcriptomics and Single-nu ## Featured Publication–Genomic analysis of a new type VI secretion system in Vibrio parahaemolyticus and its implications for environmental adaptation in shrimp ponds [Featured Publication–Genomic analysis of a new type VI secretion system in Vibrio parahaemolyticus and its implications for environmental adaptation in shrimp ponds](https://www.bmkgene.com/featured_publication/featured-publication-genomic-analysis-of-a-new-type-vi-secretion-system-in-vibrio-parahaemolyticus-and-its-implications-for-environmental-adaptation-in-shrimp-ponds/): BMKGENE provided full-length 16S rRNA absolute quantitative sequencing and analysis services for this study: Genomic analysis of a new type VI secret ## Featured Publication–Insight into the genetic basis of ammonia tolerance in razor clam Sinonovacula constricta by genome-wide association study [Featured Publication–Insight into the genetic basis of ammonia tolerance in razor clam Sinonovacula constricta by genome-wide association study](https://www.bmkgene.com/featured_publication/featured-publication-insight-into-the-genetic-basis-of-ammonia-tolerance-in-razor-clam-sinonovacula-constricta-by-genome-wide-association-study/): Razor clams (Sinonovacula constricta) are ecologically and commercially important bivalves in China. However, environmental stressors like high conce ## Featured Publication–A spatiotemporal atlas of organogenesis in the development of orchid flowers [Featured Publication–A spatiotemporal atlas of organogenesis in the development of orchid flowers](https://www.bmkgene.com/featured_publication/featured-publication-a-spatiotemporal-atlas-of-organogenesis-in-the-development-of-orchid-flowers-2/): BMKGENE provided spatial transcriptome sequencing services for this study: A spatiotemporal atlas of organogenesis in the development of orchid flowe ## Featured Publication–Whole-transcriptome RNA sequencing highlights the molecular mechanisms associated with the maintenance of postharvest quality in broccoli by red LED irradiation [Featured Publication–Whole-transcriptome RNA sequencing highlights the molecular mechanisms associated with the maintenance of postharvest quality in broccoli by red LED irradiation](https://www.bmkgene.com/featured_publication/featured-publication-whole-transcriptome-rna-sequencing-highlights-the-molecular-mechanisms-associated-with-the-maintenance-of-postharvest-quality-in-broccoli-by-red-led-irradiation/): BMKGENE is honored for providing Whole-transcriptome RNA sequencing services for this study, Whole-transcriptome RNA sequencing highlights the molecu ## Featured Publication–A Chromosome-Scale Assembly of the Asian Honeybee Apis cerana Genome [Featured Publication–A Chromosome-Scale Assembly of the Asian Honeybee Apis cerana Genome](https://www.bmkgene.com/featured_publication/featured-publication-a-chromosome-scale-assembly-of-the-asian-honeybee-apis-cerana-genome/): May 20th is World Bee Day!  Bees are essential pollinators that contribute to the diversity and productivity of ecosystems, as well as the productio ## Featured Publication–Microalgae simultaneously promote antibiotic removal and antibiotic resistance genes/bacteria attenuation in algal-bacterial granular sludge system [Featured Publication–Microalgae simultaneously promote antibiotic removal and antibiotic resistance genes/bacteria attenuation in algal-bacterial granular sludge system](https://www.bmkgene.com/featured_publication/5296/): The article, Microalgae simultaneously promote antibiotic removal and antibiotic resistance genes/bacteria attenuation in algal-bacterial granular sl ## Featured Publication–Single-cell transcriptome uncovers heterogeneity and immune responses of leukocytes after vaccination with inactivated Edwardsiella tarda in flounder (Paralichthys olivaceus) [Featured Publication–Single-cell transcriptome uncovers heterogeneity and immune responses of leukocytes after vaccination with inactivated Edwardsiella tarda in flounder (Paralichthys olivaceus)](https://www.bmkgene.com/featured_publication/featured-publication-single-cell-transcriptome-uncovers-heterogeneity-and-immune-responses-of-leukocytes-after-vaccination-with-inactivated-edwardsiella-tarda-in-flounder-paralichthys-olivace/): The article published in Aquaculture, Single-cell transcriptome uncovers heterogeneity and immune responses of leukocytes after vaccination with inac ## Featured Publication–Profile and actual transmissibility of Carbapenem resistance genes: Intracellular and extracellular DNA in hospital wastewater [Featured Publication–Profile and actual transmissibility of Carbapenem resistance genes: Intracellular and extracellular DNA in hospital wastewater](https://www.bmkgene.com/featured_publication/featured-publication-profile-and-actual-transmissibility-of-carbapenem-resistance-genes-intracellular-and-extracellular-dna-in-hospital-wastewater/): The article named "Profile and actual transmissibility of Carbapenem resistance genes: Intracellular and extracellular DNA in hospital wastewater" , ## Featured Publication–Gut microbiota-derived metabolites mediate the #neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation [Featured Publication–Gut microbiota-derived metabolites mediate the #neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation](https://www.bmkgene.com/featured_publication/featured-publication-gut-microbiota-derived-metabolites-mediate-the-neuroprotective-effect-of-melatonin-in-cognitive-impairment-induced-by-sleep-deprivation/): The article published in Microbiome, Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment indu ## Featured Publication–Detection of Chromosomal Segments Introgressed from Wild Species of Carrot into Cultivars: Quantitative Trait Loci Mapping for Morphological Features in Backcross Inbred Lines [Featured Publication–Detection of Chromosomal Segments Introgressed from Wild Species of Carrot into Cultivars: Quantitative Trait Loci Mapping for Morphological Features in Backcross Inbred Lines](https://www.bmkgene.com/featured_publication/featured-publication-detection-of-chromosomal-segments-introgressed-from-wild-species-of-carrot-into-cultivars-quantitative-trait-loci-mapping-for-morphological-features-in-backcross-inbred/): Cultivated carrot we eat nowadays is thought to have been domesticated from a wild species, and various phenotypes developed through human domestica ## Featured Publication—Riddles of Lost City: Chemotrophic Prokaryotes Drives Carbon, Sulfur, and Nitrogen Cycling at an Extinct Cold Seep, South China Sea [Featured Publication—Riddles of Lost City: Chemotrophic Prokaryotes Drives Carbon, Sulfur, and Nitrogen Cycling at an Extinct Cold Seep, South China Sea](https://www.bmkgene.com/featured_publication/featured-publication-riddles-of-lost-city-chemotrophic-prokaryotes-drives-carbon-sulfur-and-nitrogen-cycling-at-an-extinct-cold-seep-south-china-sea/): BMKGENE is honored for providing sequencing services for full-length amplicon of  bacteria and archaea for the following study: Riddles of Lost Cit ## Featured Publication--A spatiotemporal atlas of organogenesis in the development of orchid flowers [Featured Publication--A spatiotemporal atlas of organogenesis in the development of orchid flowers](https://www.bmkgene.com/featured_publication/featured-publication-a-spatiotemporal-atlas-of-organogenesis-in-the-development-of-orchid-flowers/):Great work on the first spatiotemporal atlas of floral development! In this paper, Prof. Ji-Qi's group, Fudan Univerisity, and Guoce-Chun's group, Jia ## Featured Publication--Telomere-to-telomere genome assembly of bitter melon (Momordica charantia L. var. abbreviata Ser.) reveals fruit development, composition and ripening genetic characteristics [ Featured Publication--Telomere-to-telomere genome assembly of bitter melon (Momordica charantia L. var. abbreviata Ser.) reveals fruit development, composition and ripening genetic characteristics](https://www.bmkgene.com/featured_publication/featured-publication-telomere-to-telomere-genome-assembly-of-bitter-melon-momordica-charantia-l-var-abbreviata-ser-reveals-fruit-development-composition-and-ripening-genetic-characteristics/):A Telomere-to-Telomere, high-quality Mca genome was published by Prof. Zuo-Jianhua's group, Beijing Academy of Agricultural and Forestry Sciences in H ## Featured Publication--Genomic insights into the recent chromosome reduction and polyploidization of complex autopolyploid sugarcane S. spontaneum [Featured Publication--Genomic insights into the recent chromosome reduction and polyploidization of complex autopolyploid sugarcane S. spontaneum](https://www.bmkgene.com/featured_publication/featured-publication-genomic-insights-into-the-recent-chromosome-reduction-and-polyploidization-of-complex-autopolyploid-sugarcane-s-spontaneum/):Prof. Jisen-Zhang's group from Fujian Agriculture and Forestry University published their achievements in decoding natural autotetraploid Sugarcane Np ## Featured Publication--A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand [Featured Publication--A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand](https://www.bmkgene.com/featured_publication/featured-publication-a-chromosome-scale-genome-assembly-of-mitragyna-speciosa-kratom-and-the-assessment-of-its-genetic-diversity-in-thailand/):Mitragyna speciosa (Kratom) is a narcotic plant indigenous to Southeast Asian countries, including Thailand. Traditionally, M. speciosa has been used ## Featured Publication [Featured Publication](https://www.bmkgene.com/featured_publication/featured-publication/):Featured Publication--Unraveling the influence of human fecal pollution on antibiotic resistance gene levels in different receiving water bodies using ## Featured Publication--Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds [Featured Publication--Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds](https://www.bmkgene.com/featured_publication/featured-publication-common-evolutionary-trajectory-of-short-life-cycle-in-brassicaceae-ruderal-weeds/): Conjoint analysis of genome assembly, population evolution, genetics, and molecular biology is a preferred way to tell a complete biological story of ## Featured Publication--Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii [Featured Publication--Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii](https://www.bmkgene.com/featured_publication/featured-publication-genomic-basis-of-the-giga-chromosomes-and-giga-genome-of-tree-peony-paeonia-ostii/): "In Chinese art, each month is represented by a flower, and Moutan is specifically the flower for March" -- Mark Haworth-Booth. At the beginning of M ## Featured Publication -- Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species [Featured Publication -- Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species](https://www.bmkgene.com/featured_publication/test/): Congratulations! Nature Genetics published the high-quality research on tomato Pan-genome on April 6, 2023, which was led by Horticultural Crops Rese ## news link [news](https://www.bmkgene.com/news/) ## BMKGENE to Present Spatial Genomics Solutions at ESEB 2025 – Europe's Flagship Evolutionary Biology Congress [BMKGENE to Present Spatial Genomics Solutions at ESEB 2025 – Europe's Flagship Evolutionary Biology Congress](https://www.bmkgene.com/news/bmkgene-to-present-spatial-genomics-solutions-at-eseb-2025-europes-flagship-evolutionary-biology-congress/): Barcelona, Spain | August 17–22, 2025 | Booth #3   Biomarker Technologies (BMKGENE) will join the 18th ESEB Congress – Europe’s premier ## BMKGENE helps ETH Zurich achieve a major breakthrough in endosymbiosis research [BMKGENE helps ETH Zurich achieve a major breakthrough in endosymbiosis research](https://www.bmkgene.com/news/bmkgene-helps-eth-zurich-achieve-a-major-breakthrough-in-endosymbiosis-research/):Endosymbiosis has had a profound impact on the evolution of life, endowing organisms with new biochemical capabilities and promoting innovation and di ## BMKGENE Makes a Splash at the 32nd Plant and Animal Genome Conference in San Diego [BMKGENE Makes a Splash at the 32nd Plant and Animal Genome Conference in San Diego](https://www.bmkgene.com/news/bmkgene-makes-a-splash-at-the-32nd-plant-and-animal-genome-conference-in-san-diego/):From January 10 - 15, 2025, the world's preeminent researchers in plant and animal genomics convened in San Diego, USA, for the 32nd Plant and Animal ## BMKGENE 2024: Innovation, Progress, and a Bright Future Ahead [BMKGENE 2024: Innovation, Progress, and a Bright Future Ahead](https://www.bmkgene.com/news/bmkgene-2024-innovation-progress-and-a-bright-future-ahead/):As we look back on the year 2024, BMKGENE reflects on a remarkable journey of innovation, progress, and unwavering dedication to the scientific commun ## Christmas Cheers and Gratitude: Reflecting on the Past Year with BMKGENE [Christmas Cheers and Gratitude: Reflecting on the Past Year with BMKGENE](https://www.bmkgene.com/news/christmas-cheers-and-gratitude-reflecting-on-the-past-year-with-bmkgene/):As Christmas approaches, it’s a perfect time to reflect on the year gone by, express gratitude, and celebrate the connections that have made this ye ## Meet Our Mascot: Dr. Bio – A Symbol of Innovation and Curiosity! [Meet Our Mascot: Dr. Bio – A Symbol of Innovation and Curiosity!](https://www.bmkgene.com/news/meet-our-mascot-dr-bio-a-symbol-of-innovation-and-curiosity/): We are thrilled to introduce a new addition to our team, someone who embodies the spirit of discovery, intelligence, and collaboration –Dr. Bio! W ## ASHG 2024 - The American Society of Human Genetics [ASHG 2024 - The American Society of Human Genetics](https://www.bmkgene.com/news/ashg-2024-the-american-society-of-human-genetics/): We are excited to announce that BMKGENE will be participating in the American Society of Human Genetics (ASHG) 2024 conference, taking place from Nov ## ASM Microbe 2024 — American Society for Microbiology [ASM Microbe 2024 — American Society for Microbiology](https://www.bmkgene.com/news/asm-microbe-2024-american-society-for-microbiology/):   ASM Microbe 2024 is coming. As a company dedicated to exploring the mysteries of genes and providing the forefront biotechnology services, BMK ## EACR 2024 — The European Association for Cancer Research [EACR 2024 — The European Association for Cancer Research](https://www.bmkgene.com/news/eacr-2024-the-european-association-for-cancer-research/):  EACR2024 is about to open in Rotterdam Netherlands at June 10th-13th. As service provider in the field of biotechnology, BMKGENE will bring elite a ## ESHG 2024 — The European Human Genetics Conference [ESHG 2024 — The European Human Genetics Conference](https://www.bmkgene.com/news/eshg2024/):   ESHG2024 will be opened from June 1st to June 4th, 2024 at Berlin, Germany. BMKGENE is waiting for you at booth #426! As the most influential ## Biomarker Technologies and TIANGEN Biotech signed a strategic cooperation agreement in the European market [Biomarker Technologies and TIANGEN Biotech signed a strategic cooperation agreement in the European market](https://www.bmkgene.com/news/beijing-biomarker-technologies-and-tiangen-biotech-signed-a-strategic-cooperation-agreement-in-the-european-market/):  Biomarker Technologies and TIANGEN Biotech signed a strategic cooperation agreement in the European market On February 5, 2024, Biomarker Techn ## Proud to be selected as one of the Top 10 Genomic Solutions Companies in Europe for 2023! [Proud to be selected as one of the Top 10 Genomic Solutions Companies in Europe for 2023!](https://www.bmkgene.com/news/proud-to-be-selected-as-one-of-the-top-10-genomic-solutions-companies-in-europe-for-2023/): Proud to be selected as one of the Top 10 Genomic Solutions Companies in Europe for 2023!  BMKGENE is excited to announce that our company has been ## Neuroscience Singapore 2023 [Neuroscience Singapore 2023 ](https://www.bmkgene.com/news/neuroscience-singapore-2023/): Join Us at the Upcoming Exhibition: Neuroscience Singapore 2023 ! The upcoming Neuroscience Singapore 2023 symposium, in collaboration with the Ins ## 10th Edition of the i3S Annual Meeting [10th Edition of the i3S Annual Meeting](https://www.bmkgene.com/news/10th-edition-of-the-i3s-annual-meeting/): We’re glad to be at the 10th i3S Annual Meeting, which will be held on the 16th and 17th of November at the Axis Vermar Conference & Beach Hote ## 9th Plant Genomics & Gene Editing Congress Asia [9th Plant Genomics & Gene Editing Congress Asia](https://www.bmkgene.com/news/9th-plant-genomics-gene-editing-congress-asia/): We are pleased to announce that BMKGENE will be sponsoring the <9th Plant Genomics & Gene Editing Congress Asia> in Thailand! This conferen ## 33rd MSPPC—Malaysian Society of Plant Physiology Conference 2023 [33rd MSPPC—Malaysian Society of Plant Physiology Conference 2023](https://www.bmkgene.com/news/33rd-msppc-malaysian-society-of-plant-physiology-conference-2023/): Join Us at the Upcoming Exhibition: 33rd MSPPC！BMKGENE is excited to announce our participation in <Malaysian Society of Plant Physiology Confer ## PAG2023—International Plant and Animal Genome Conference Australia [PAG2023—International Plant and Animal Genome Conference Australia](https://www.bmkgene.com/news/pag2023-international-plant-and-animal-genome-conference-australia/): Join Us at the Upcoming Exhibition: PAG Australia 2023! BMKGENE is excited to announce our participation in <International Plant and Animal Genom ## ICPP2023—12TH INTERNATIONAL CONGRESS OF PLANT PATHOLOGY [ICPP2023—12TH INTERNATIONAL CONGRESS OF PLANT PATHOLOGY](https://www.bmkgene.com/news/icpp2023-12th-international-congress-of-plant-pathology/): BMKGENE will be attending the 12TH INTERNATIONAL CONGRESS OF PLANT PATHOLOGY in Lyon, France! We will show our One-stop high-throughput sequencing a ## SMBE2023—the 2023 annual Society of Molecular Biology and Evolution conference [SMBE2023—the 2023 annual Society of Molecular Biology and Evolution conference](https://www.bmkgene.com/news/smbe2023-the-2023-annual-society-of-molecular-biology-and-evolution-conference/): BMKGENE will be attending the 2023 annual Society of Molecular Biology and Evolution conference in Ferrara, Italy! SMBE is a global scientific associ ## FEMS2023 conference—The 10th Congress of European Microbiologists [FEMS2023 conference—The 10th Congress of European Microbiologists](https://www.bmkgene.com/news/fems2023-conference-the-10th-congress-of-european-microbiologists/): BMKGENE will be attending the #FEMS2023 conference. (The 10th Congress of European Microbiologists).Welcome to visit us at Booth C5! We have prep ## ESHG 2023 —The European Human Genetics Conference [ESHG 2023 —The European Human Genetics Conference](https://www.bmkgene.com/news/eshg2023-the-european-human-genetics-conference/): BMKGENE will be participating in ESHG 2023 from June 10th to June 13th, 2023 at Glasgow, Scotland, UK. In this conference, BMKGENE will present our c ## The 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023) [The 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023)](https://www.bmkgene.com/news/the-33rd-european-congress-of-clinical-microbiology-infectious-diseases-eccmid-2023/): We’re excited to be attending ECCMID 2023 next week on 15-18 April, in Copenhagen, Denmark. In this exhibition, BMKGENE will present our compreh ## Festival of Genomics & Biodata 2023 (FOG) [Festival of Genomics & Biodata 2023 (FOG)](https://www.bmkgene.com/news/festival-of-genomics-biodata-2023-fog/):The largest genomics event-- Festival of Genomics and Biodata 2023 is back in-person at the Business Design Centre, London, United Kingdom, on 25-26 ## 【News&Highlights】Biomarker Technologies Witnessed 31 Successful De novo Genome Research in 2021 [【News&Highlights】Biomarker Technologies Witnessed 31 Successful De novo Genome Research in 2021](https://www.bmkgene.com/news/newshighlights-biomarker-technologies-witnessed-31-successful-de-novo-genome-research-in-2021/):In 2021,  BMKGENE witnessed 31 De novo genome research successfully published in high-impact journals with total impact factors over 320. 15 of t ## Webinar: Start Your First Spatial Transcriptome Sequencing Study? 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Our speakers will give an in- ## Seadragon genome analysis provides insights into its phenotype and sex determination locus [Seadragon genome analysis provides insights into its phenotype and sex determination locus](https://www.bmkgene.com/news/seadragon-genome-analysis-provides-insights-into-its-phenotype-and-sex-determination-locus/): GENOME EVOLUTION Genome De novo Assembly|Sex determination The whole sequencing works and partial bioinformatic services were provided by Bioma ## Application of Nanopore full-length transcriptome sequencing in isoform-level AS study [Application of Nanopore full-length transcriptome sequencing in isoform-level AS study](https://www.bmkgene.com/news/application-of-nanopore-full-length-transcriptome-sequencing-in-isoform-level-as-study/): TRANSCRIPTOMICS natureCOMMUNICATIONS Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals down ## Latest successful cases on Nanopore RNA-Sequencing with Biomarker Technologies [Latest successful cases on Nanopore RNA-Sequencing with Biomarker Technologies](https://www.bmkgene.com/news/latest-successful-cases-on-nanopore-rna-sequencing-with-biomarker-technologies/): Nanopore-based Full-length Transcriptome Sequencing Nanopore sequencing distinguishes itself from other sequencing platforms, in that the nucleo ## Application of full-length amplicon sequencing in microbial diversity studies [Application of full-length amplicon sequencing in microbial diversity studies](https://www.bmkgene.com/news/application-of-full-length-amplicon-sequencing-in-microbial-diversity-studies/): MICROBIAL ECOLOGY Agricultural intensification reduces microbial network complexity and the abundance of keystone taxa in roots Full-length ## Investigation of microbiome community and function in immobilized bacteria treated soil by full-length 16S sequencing [Investigation of microbiome community and function in immobilized bacteria treated soil by full-length 16S sequencing](https://www.bmkgene.com/news/investigation-of-microbiome-community-and-function-in-immobilized-bacteria-treated-soil-by-full-length-16s-sequencing/): MICROBIAL Bacterial compatibility and immobilization with biochar improved tebuconazole degradation, soil microbiome composition and functi ## Performance of nanopore long reads in metagenomic studies [Performance of nanopore long reads in metagenomic studies](https://www.bmkgene.com/news/performance-of-nanopore-long-reads-in-metagenomic-studies/): METAGENOMICS Complete, closed bacterial genomes from microbiomes using nanopore sequencing Nanopore Sequencing | Metagenomics | MAGs | B ## Application of Nanopore long-read resequencing in the fight against disease [Application of Nanopore long-read resequencing in the fight against disease](https://www.bmkgene.com/news/application-of-nanopore-long-read-resequencing-in-the-fight-against-disease/): HUMAN GENOMICS nature genetics Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inc ## Application of Nanopore-based re-sequencing in COVID19 genetic variants identification [Application of Nanopore-based re-sequencing in COVID19 genetic variants identification](https://www.bmkgene.com/news/application-of-nanopore-based-re-sequencing-in-covid19-genetic-varia