# Avance Clinical > Avance Clinical is a full-service Contract Research Organization (CRO) headquartered in Australia, with clinical operations across North America, Asia Pacific, China and Europe, and more than 30 years of clinical research management experience. Markdown versions of each page are available by appending index.md to the page URL. ## Home - [Australia-Based CRO for Biotechs | Go Global | Avance Clinical](https://www.avancecro.com/) ([markdown](https://www.avancecro.com/index.md)) ## Clinical Research Solutions - [Preclinical CRO for Biotechs | ClinicReady | Avance Clinical](https://www.avancecro.com/cro/preclinical-clinicready/) ([markdown](https://www.avancecro.com/cro/preclinical-clinicready/index.md)): ClinicReady is your preclinical CRO — gap analysis, IND-enabling studies, regulatory submissions, and clinical trial design from PhD-qualified specialists. - [Global CRO Model for Biotech Drug Development | GlobalReady | Avance Clinical](https://www.avancecro.com/cro/globalready/) ([markdown](https://www.avancecro.com/cro/globalready/index.md)): Your full-lifecycle global CRO model spanning early-phase clinical R&D in Australia, with pathways to North America, Asia Pacific, and Europe. - [Phase I / Early Phase](https://www.avancecro.com/cro/phase-i-early-phase/) ([markdown](https://www.avancecro.com/cro/phase-i-early-phase/index.md)): Run your Phase I or Phase II trial with a CRO whose data is accepted by the FDA and EMA and that has guided 700+ emerging biotechs. - [Phase II / Late Phase](https://www.avancecro.com/cro/phase-ii-late-phase/) ([markdown](https://www.avancecro.com/cro/phase-ii-late-phase/index.md)): Moving from early to late phase? Avance Clinical brings the same expertise to multi-regional studies across Australia, Asia, North America & Europe. ## Why Avance Clinical - [Why Avance Clinical for Early Phase Clinical Trials in Australia](https://www.avancecro.com/why-avance-clinical-for-early-phase-clinical-trials-in-australia/) ([markdown](https://www.avancecro.com/why-avance-clinical-for-early-phase-clinical-trials-in-australia/index.md)): 30+ years guiding biotechs through Early Phase trials in Australia: a leading Phase I team, regulatory support and a robust site network. - [The Australian Advantage](https://www.avancecro.com/the-australian-advantage/) ([markdown](https://www.avancecro.com/the-australian-advantage/index.md)): Start your trial in Australia in 5-6 weeks with no IND required, plus up to 43.5% back on R&D spend. See how the Australian Advantage works. - [The North American Advantage](https://www.avancecro.com/the-north-american-advantage/) ([markdown](https://www.avancecro.com/the-north-american-advantage/index.md)): Avance Clinical is the largest specialist Australian and US CRO delivering quality clinical trials in Australia, New Zealand and North America for international biotechs. - [The Asia Advantage](https://www.avancecro.com/the-asia-advantage/) ([markdown](https://www.avancecro.com/the-asia-advantage/index.md)): Avance Clinical is the largest specialist Australian and US CRO delivering quality clinical trials in Australia, New Zealand and North America for international biotechs. - [The EU Advantage](https://www.avancecro.com/the-eu-advantage/) ([markdown](https://www.avancecro.com/the-eu-advantage/index.md)): Start your early-phase studies in Australia to gain regulatory speed, scientific flexibility, and significant cost efficiencies - then seamlessly expand globally with the same expert team. - [Technology](https://www.avancecro.com/cro/technology/) ([markdown](https://www.avancecro.com/cro/technology/index.md)): Our Technology Innovation team is focussed on identifying and assessing new technology designed to accelerate high quality clinical research programs. ## Centers of Excellence - [Early Phase Center of Excellence for Biotechs](https://www.avancecro.com/early-phase-center-of-excellence-for-biotechs/) ([markdown](https://www.avancecro.com/early-phase-center-of-excellence-for-biotechs/index.md)): A leader in early phase for 30+ years, Avance Clinical's Early Phase Center of Excellence co-designs your first-in-human study before execution begins. - [Expert Clinical Trial Services in Neuroscience – Transforming CNS clinical research for biotech innovation](https://www.avancecro.com/expert-clinical-trial-services-in-neuroscience/) ([markdown](https://www.avancecro.com/expert-clinical-trial-services-in-neuroscience/index.md)): Taking a CNS therapy from first-in-human to Phase III? Avance Clinical's CNS Center of Excellence is led by medical and scientific experts. - [Oncology Center of Excellence](https://www.avancecro.com/oncology-center-of-excellence/) ([markdown](https://www.avancecro.com/oncology-center-of-excellence/index.md)): Smarter early phase oncology: Avance Clinical's Oncology Center of Excellence brings adaptive dose-escalation design and senior oncology leadership. - [Renal & Cardiometabolic Center of Excellence](https://www.avancecro.com/renal-cardiometabolic-center-of-excellence/) ([markdown](https://www.avancecro.com/renal-cardiometabolic-center-of-excellence/index.md)): Accurate, high-quality trial data: Avance Clinical's in-house data management team handles e-CRF build, edit checks, MedDRA coding and data cleaning. ## Capabilities - [Our capabilities](https://www.avancecro.com/capabilities/our-capabilities/) ([markdown](https://www.avancecro.com/capabilities/our-capabilities/index.md)): Full-service CRO for biotechs: clinical operations, data management, biostatistics, medical writing, safety, patient recruitment and regulatory affairs. - [Clinical operations](https://www.avancecro.com/capabilities/clinical-operations/) ([markdown](https://www.avancecro.com/capabilities/clinical-operations/index.md)): Clinical operations across all phases and regions: a dedicated Project Manager as your single contact, plus site selection, monitoring and vendor oversight. - [Data Management](https://www.avancecro.com/capabilities/data-management/) ([markdown](https://www.avancecro.com/capabilities/data-management/index.md)): Accurate, high-quality trial data: Avance Clinical's in-house data management team handles e-CRF build, edit checks, MedDRA coding and data cleaning. - [Biostatistics](https://www.avancecro.com/capabilities/biostatistics/) ([markdown](https://www.avancecro.com/capabilities/biostatistics/index.md)): Need rapid PK analysis for interim decisions? Avance Clinical's biostatistics team also builds CDISC-compliant SDTM and ADaM datasets. - [Medical Writing](https://www.avancecro.com/capabilities/medical-writing/) ([markdown](https://www.avancecro.com/capabilities/medical-writing/index.md)): PhD-qualified medical writers with 20+ years' average experience draft your protocols, investigator brochures, CSRs and INDs to ICH standards. - [Quality assurance](https://www.avancecro.com/capabilities/quality-assurance/) ([markdown](https://www.avancecro.com/capabilities/quality-assurance/index.md)): Catch quality issues early. Avance Clinical's independent quality assurance team audits your sites, vendors and data, from preclinical through to market. - [Patient Recruitment](https://www.avancecro.com/capabilities/patient-recruitment/) ([markdown](https://www.avancecro.com/capabilities/patient-recruitment/index.md)): Boost enrolment and retention: Avance Clinical pairs experienced sites with disease-specific advocacy groups and patient registries. - [Global Scientific & Regulatory Affairs](https://www.avancecro.com/capabilities/global-scientific-regulatory-affairs/) ([markdown](https://www.avancecro.com/capabilities/global-scientific-regulatory-affairs/index.md)): Unlock regulatory success with Avance Clinical’s global scientific and regulatory affairs department. Your surrogate development department. Avance Clinical's scientific and regulatory affairs team plans your regulatory strategy and liaises with authorities. - [Global site partnership network](https://www.avancecro.com/capabilities/avance-clinicals-global-site-partnership-network/) ([markdown](https://www.avancecro.com/capabilities/avance-clinicals-global-site-partnership-network/index.md)): Avance Clinical's 2,000+ site network spans Australia, New Zealand, the US and Canada, with centralized contracts and IRBs for rapid activation. - [Safety and Pharmacovigilance](https://www.avancecro.com/capabilities/safety-and-pharmacovigilance/) ([markdown](https://www.avancecro.com/capabilities/safety-and-pharmacovigilance/index.md)): Protect participants and data integrity: Avance Clinical's multi-disciplinary safety team delivers pharmacovigilance monitoring and reporting. ## Therapeutic Areas - [Biotech experience](https://www.avancecro.com/therapeutic-areas/biotech-experience/) ([markdown](https://www.avancecro.com/therapeutic-areas/biotech-experience/index.md)): Avance Clinical has worked across 250+ therapeutic indications in three decades, offering biotechs one full-service partner, not a single-disease specialist. - [Specialist areas](https://www.avancecro.com/therapeutic-areas/specialist-areas/) ([markdown](https://www.avancecro.com/therapeutic-areas/specialist-areas/index.md)): See Avance Clinical's specialist expertise across multiple therapeutic areas, from CNS and oncology to dermatology and rare disease. - [Central nervous system (CNS)](https://www.avancecro.com/therapeutic-areas/central-nervous-system-cns/) ([markdown](https://www.avancecro.com/therapeutic-areas/central-nervous-system-cns/index.md)): Avance Clinical has run 50+ CNS trials in five years across 33 indications, from Alzheimer's to epilepsy, backed by in-house medical expertise. - [Oncology](https://www.avancecro.com/therapeutic-areas/oncology/) ([markdown](https://www.avancecro.com/therapeutic-areas/oncology/index.md)): Avance Clinical has run 260+ oncology trials across 16 cancer types, backed by a dedicated Oncology Center of Excellence. - [Dermatology](https://www.avancecro.com/therapeutic-areas/dermatology/) ([markdown](https://www.avancecro.com/therapeutic-areas/dermatology/index.md)): Avance Clinical runs dermatology trials across psoriasis, atopic dermatitis, alopecia and cosmetic indications, backed by Medidata-certified specialists. - [Endocrinology](https://www.avancecro.com/therapeutic-areas/endocrinology/) ([markdown](https://www.avancecro.com/therapeutic-areas/endocrinology/index.md)): Avance Clinical runs endocrinology trials across diabetes, thyroid disorders, obesity and rare conditions like congenital adrenal hyperplasia. - [Infectious diseases](https://www.avancecro.com/therapeutic-areas/infectious-diseases/) ([markdown](https://www.avancecro.com/therapeutic-areas/infectious-diseases/index.md)): Avance Clinical runs infectious disease trials across 11 indications, from HIV and hepatitis to COVID-19 and antibiotic resistance. - [Ophthalmology](https://www.avancecro.com/therapeutic-areas/ophthalmology/) ([markdown](https://www.avancecro.com/therapeutic-areas/ophthalmology/index.md)): Avance Clinical runs ophthalmology trials in macular degeneration, dry eye disease and glaucoma, drawing on three decades of drug development experience. - [Rare disease & orphan drug](https://www.avancecro.com/therapeutic-areas/rare-disease-orphan-drug/) ([markdown](https://www.avancecro.com/therapeutic-areas/rare-disease-orphan-drug/index.md)): Avance Clinical has partnered with patient advocacy groups on 60+ rare disease trials across 28 indications, from Fragile X to Duchenne dystrophy. - [Respiratory & allergy](https://www.avancecro.com/therapeutic-areas/respiratory-allergy/) ([markdown](https://www.avancecro.com/therapeutic-areas/respiratory-allergy/index.md)): Avance Clinical runs respiratory and allergy trials across COPD, asthma and idiopathic pulmonary fibrosis, backed by Medidata-trained specialists. ## About - [About Us](https://www.avancecro.com/about-avance-clinical-cro/) ([markdown](https://www.avancecro.com/about-avance-clinical-cro/index.md)): One CRO for your whole program, preclinical to late phase. Avance Clinical is a global biotech CRO based in Australia with 30+ years' experience. - [Meet the team](https://www.avancecro.com/meet-the-team/) ([markdown](https://www.avancecro.com/meet-the-team/index.md)): Meet the scientific, regulatory, operations & commercial leaders guiding Avance Clinical, averaging 21 years of industry experience. - [Awards](https://www.avancecro.com/industry-awards/) ([markdown](https://www.avancecro.com/industry-awards/index.md)): Avance Clinical has won Frost & Sullivan's Customer Value Leadership Award every year since 2021, most recently as 2026 Global Company of the Year. - [Locations](https://www.avancecro.com/locations/) ([markdown](https://www.avancecro.com/locations/index.md)): We're growing! Avance Clinical is a global CRO for biotechs with offices in Australia, North America, India and Asia. See all our locations. - [Careers](https://www.avancecro.com/careers/) ([markdown](https://www.avancecro.com/careers/index.md)): Browse open roles at Avance Clinical, a full-service CRO, and join a diverse, inclusive team of 450+ people from across the globe. - [Working at Avance Clinical](https://www.avancecro.com/working-at-avance-clinical/) ([markdown](https://www.avancecro.com/working-at-avance-clinical/index.md)): Avance Clinical's remote-first culture spans five continents: supportive, flexible and built on respect, integrity, responsibility and innovation. ## Contact - [Contact](https://www.avancecro.com/contact-us/) ([markdown](https://www.avancecro.com/contact-us/index.md)): Contact Avance Clinical about your trial. Reach our global teams in Australia, North America, Asia and Europe, or book a meeting. - [Request A Proposal](https://www.avancecro.com/request-a-proposal/) ([markdown](https://www.avancecro.com/request-a-proposal/index.md)): Request a proposal for your preclinical, Phase I or Phase II/III biotech trial in Australia, New Zealand or North America. - [Book a meeting](https://www.avancecro.com/book-a-meeting/) ([markdown](https://www.avancecro.com/book-a-meeting/index.md)): Please book a meeting to speak with our business development team at an upcoming conference, event or roadshow. ## Optional - [Sitemap index](https://www.avancecro.com/sitemap_index.xml)